Abstract
Whether hyperthyroidism can cause a dilated cardiomyopathy remains controversial. It has been generally accepted that thyrotoxicosis may be associated with high output heart failure and may precipitate ischemia or heart failure in patients with either symptomatic or asymptomatic underlying heart disease. However, evidence for the development of a dilated cardiomyopathy in otherwise normal hearts is confined to animal models and the pediatric population.1 Studies showing a decreased cardiac reserve on exercise by nuclear cardiographic studies are often quoted as evidence of occult myocardial dysfunction in hyperthyroid patients. The number of patients in these studies was small and predominantly female (15 of 19).2,3 The fact that women do not consistently increase their ejection fraction with exercise4 challenges the current interpretation of these results. We present a patient in whom thyrotoxicosis was accompanied by a reversible dilated cardiomyopathy.
| Original language | English |
|---|---|
| Journal | The American journal of cardiology |
| Volume | 70 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 1 1992 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Reversible dilated cardiomyopathy due to thyrotoxicosis. / Bauerlein, Eugene; Chakko, C. Simon; Kessler, Kenneth M.
In: The American journal of cardiology, Vol. 70, No. 1, 01.07.1992.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reversible dilated cardiomyopathy due to thyrotoxicosis
AU - Bauerlein, Eugene
AU - Chakko, C. Simon
AU - Kessler, Kenneth M.
PY - 1992/7/1
Y1 - 1992/7/1
N2 - Whether hyperthyroidism can cause a dilated cardiomyopathy remains controversial. It has been generally accepted that thyrotoxicosis may be associated with high output heart failure and may precipitate ischemia or heart failure in patients with either symptomatic or asymptomatic underlying heart disease. However, evidence for the development of a dilated cardiomyopathy in otherwise normal hearts is confined to animal models and the pediatric population.1 Studies showing a decreased cardiac reserve on exercise by nuclear cardiographic studies are often quoted as evidence of occult myocardial dysfunction in hyperthyroid patients. The number of patients in these studies was small and predominantly female (15 of 19).2,3 The fact that women do not consistently increase their ejection fraction with exercise4 challenges the current interpretation of these results. We present a patient in whom thyrotoxicosis was accompanied by a reversible dilated cardiomyopathy.
AB - Whether hyperthyroidism can cause a dilated cardiomyopathy remains controversial. It has been generally accepted that thyrotoxicosis may be associated with high output heart failure and may precipitate ischemia or heart failure in patients with either symptomatic or asymptomatic underlying heart disease. However, evidence for the development of a dilated cardiomyopathy in otherwise normal hearts is confined to animal models and the pediatric population.1 Studies showing a decreased cardiac reserve on exercise by nuclear cardiographic studies are often quoted as evidence of occult myocardial dysfunction in hyperthyroid patients. The number of patients in these studies was small and predominantly female (15 of 19).2,3 The fact that women do not consistently increase their ejection fraction with exercise4 challenges the current interpretation of these results. We present a patient in whom thyrotoxicosis was accompanied by a reversible dilated cardiomyopathy.
UR - http://www.scopus.com/inward/record.url?scp=0026724750&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026724750&partnerID=8YFLogxK
U2 - 10.1016/0002-9149(92)91412-W
DO - 10.1016/0002-9149(92)91412-W
M3 - Article
C2 - 1303624
AN - SCOPUS:0026724750
VL - 70
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 1
ER -