Revascularization after intravitreal bevacizumab and laser therapy of bilateral retinal vascular occlusions in incontinentia pigmenti (Bloch-Sulzberger syndrome)

Linda A. Cernichiaro-Espinosa, Nimesh A. Patel, Mislen S. Bauer, Catherin I. Negron, Brenda Fallas, Alexander Pogrebniak, Audina Berrocal

Research output: Contribution to journalArticle


No consensus exists for the treatment of retinopathy in incontinentia pigmenti (IP). Vascular ischemia leads to tractional retinal detachments if untreated. Ultra-widefield fluorescein angiography (FA) is used to follow the vascular status of the retina. A 13-week-old female with IP presented with bilateral retinal vascular occlusions in both eyes. Ultra-widefield FA showed reperfusion after treatment with intravitreal bevacizumab (IVB) and angiography-guided laser to the avascular retina. Anti-vascular endothelial growth factor treatment reduces neovascularization and allows for growth of retinal vessels. IVB and FA-guided laser to the avascular retina is an option in IP.

Original languageEnglish (US)
Pages (from-to)E33-E37
JournalOphthalmic Surgery Lasers and Imaging Retina
Issue number2
StatePublished - Feb 1 2019


ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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