Retroviral etiology of the acquired immune deficiency syndrome (AIDS).

D. J. Volsky, K. Sakai, Mario Stevenson, S. Dewhurst

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The acquired immune deficiency syndrome (AIDS) is characterized by severe immunological defects resulting in opportunistic infections and malignancies. A novel human retrovirus, known under the terms of LAV, HTLV-III, ARV or as a human immunodeficiency virus (HIV), has been defined as the infectious agent responsible for the induction of the immunologic disorders in AIDS. However, two recent lines of evidence, reviewed in this article, complicate the etiological picture of AIDS: the HIV family appears to consist of a great number of diverse, and perhaps diversifying in vivo, members that exhibit different molecular and biological properties; the human retrovirus family may contain yet another distinct class of member viruses that resemble HIV morphologically and structurally but may differ in their pathogenicity. Our understanding of the retroviral etiology of AIDS may be far from complete.

Original languageEnglish
JournalAIDS Research
Volume2 Suppl 1
StatePublished - Dec 1 1986
Externally publishedYes

Fingerprint

Acquired Immunodeficiency Syndrome
HIV
Retroviridae
Opportunistic Infections
Virulence
Viruses
Neoplasms

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Retroviral etiology of the acquired immune deficiency syndrome (AIDS). / Volsky, D. J.; Sakai, K.; Stevenson, Mario; Dewhurst, S.

In: AIDS Research, Vol. 2 Suppl 1, 01.12.1986.

Research output: Contribution to journalArticle

Volsky, D. J. ; Sakai, K. ; Stevenson, Mario ; Dewhurst, S. / Retroviral etiology of the acquired immune deficiency syndrome (AIDS). In: AIDS Research. 1986 ; Vol. 2 Suppl 1.
@article{0334a1a99ed8402c95c4cd2d8654f80f,
title = "Retroviral etiology of the acquired immune deficiency syndrome (AIDS).",
abstract = "The acquired immune deficiency syndrome (AIDS) is characterized by severe immunological defects resulting in opportunistic infections and malignancies. A novel human retrovirus, known under the terms of LAV, HTLV-III, ARV or as a human immunodeficiency virus (HIV), has been defined as the infectious agent responsible for the induction of the immunologic disorders in AIDS. However, two recent lines of evidence, reviewed in this article, complicate the etiological picture of AIDS: the HIV family appears to consist of a great number of diverse, and perhaps diversifying in vivo, members that exhibit different molecular and biological properties; the human retrovirus family may contain yet another distinct class of member viruses that resemble HIV morphologically and structurally but may differ in their pathogenicity. Our understanding of the retroviral etiology of AIDS may be far from complete.",
author = "Volsky, {D. J.} and K. Sakai and Mario Stevenson and S. Dewhurst",
year = "1986",
month = "12",
day = "1",
language = "English",
volume = "2 Suppl 1",
journal = "AIDS Research and Human Retroviruses",
issn = "0889-2229",
publisher = "Mary Ann Liebert Inc.",

}

TY - JOUR

T1 - Retroviral etiology of the acquired immune deficiency syndrome (AIDS).

AU - Volsky, D. J.

AU - Sakai, K.

AU - Stevenson, Mario

AU - Dewhurst, S.

PY - 1986/12/1

Y1 - 1986/12/1

N2 - The acquired immune deficiency syndrome (AIDS) is characterized by severe immunological defects resulting in opportunistic infections and malignancies. A novel human retrovirus, known under the terms of LAV, HTLV-III, ARV or as a human immunodeficiency virus (HIV), has been defined as the infectious agent responsible for the induction of the immunologic disorders in AIDS. However, two recent lines of evidence, reviewed in this article, complicate the etiological picture of AIDS: the HIV family appears to consist of a great number of diverse, and perhaps diversifying in vivo, members that exhibit different molecular and biological properties; the human retrovirus family may contain yet another distinct class of member viruses that resemble HIV morphologically and structurally but may differ in their pathogenicity. Our understanding of the retroviral etiology of AIDS may be far from complete.

AB - The acquired immune deficiency syndrome (AIDS) is characterized by severe immunological defects resulting in opportunistic infections and malignancies. A novel human retrovirus, known under the terms of LAV, HTLV-III, ARV or as a human immunodeficiency virus (HIV), has been defined as the infectious agent responsible for the induction of the immunologic disorders in AIDS. However, two recent lines of evidence, reviewed in this article, complicate the etiological picture of AIDS: the HIV family appears to consist of a great number of diverse, and perhaps diversifying in vivo, members that exhibit different molecular and biological properties; the human retrovirus family may contain yet another distinct class of member viruses that resemble HIV morphologically and structurally but may differ in their pathogenicity. Our understanding of the retroviral etiology of AIDS may be far from complete.

UR - http://www.scopus.com/inward/record.url?scp=0022832547&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022832547&partnerID=8YFLogxK

M3 - Article

C2 - 2881556

AN - SCOPUS:0022832547

VL - 2 Suppl 1

JO - AIDS Research and Human Retroviruses

JF - AIDS Research and Human Retroviruses

SN - 0889-2229

ER -