Retrocorneal fixation keratoprosthes1s: Analysis of 59 patients with up to 7 years of follow-up

J. M. Parel, E. Lacombe

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose Analyse the outcome, determine the cause for failure, and define the characteristics and parameters of an improved keratoprosthesis Methods A 2-piece PMMA retro-corneal fixation device designed for implantation in a single procedure in phakic and aphakic eyes was tested /// vitro and implanted in 59 patients having only light perception (LP) 20 had pseudo-pemphigus, 16 severe corneal burns, 11 trachoma, 6 pseudo phakic bullous keratopathy, and 6 multiple graft failures Results Extrusion of the prosthesis in vitro did not occur even with IOP as high as 2,000 mmHg In patients, at one month, 58 eyes had retained the KPro; 19 had no vision improvement and 39 had visual acuities (VA) of 20/400 to 20/20. At the last examination (avg 35 months), 45 eyes had retained their prosthesis, 13 had LP, 32 had a VA of 20/400 to 20/25 and 13 patients lost their prosthesis and their eye Thus far, the life-time of this prosthesis is >42.8 months (range 0 5 to 84 months) Conclusion Preliminary results are encouraging Retrocorneal fixation reduces the number and rate of postoperative complications. Based on the above experience, flexibility and two improved sealing systems were added to the next generation prosthesis to further increase the overall survival rate.

Original languageEnglish (US)
Pages (from-to)S131
JournalInvestigative Ophthalmology and Visual Science
Issue number4
StatePublished - Dec 1 1997
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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