Retinopathy of prematurity. Diagnosis, severity, and natural history

J. T. Flynn, Eduardo Bancalari, B. N. Bachynski, E. B. Buckley, R. Bawol, R. Goldberg, J. Cassady, J. Schiffman, William J Feuer, D. Gillings

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Abstract

This article presents data gathered in a prospective clinical trial of constant monitoring of oxygen therapy on the diagnosis, severity (as coded by a severity index [SI]) and natural history of retinopathy of prematurity (ROP) in 214 surviving infants with birthweights less than or equal to 1300 g. ROP developed in 119 (55.6%) infants and, of these, cicatricial ROP developed in nine (7.6%). The disease was diagnosed at 8-9 weeks on the average in infants with birthweights less than 900 g and 4-5 weeks in infants 900 to 1300 g. Those infants in whom the disease regressed, ROP lasted approximately 15 weeks. The severity of the disease, as defined by the SI, was strongly correlated with the birthweight of the infant and weakly correlated with the total duration of oxygen therapy.

Original languageEnglish
Pages (from-to)620-629
Number of pages10
JournalOphthalmology
Volume94
Issue number6
StatePublished - Aug 6 1987

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Retinopathy of Prematurity
Natural History
Oxygen
Clinical Trials
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Flynn, J. T., Bancalari, E., Bachynski, B. N., Buckley, E. B., Bawol, R., Goldberg, R., ... Gillings, D. (1987). Retinopathy of prematurity. Diagnosis, severity, and natural history. Ophthalmology, 94(6), 620-629.

Retinopathy of prematurity. Diagnosis, severity, and natural history. / Flynn, J. T.; Bancalari, Eduardo; Bachynski, B. N.; Buckley, E. B.; Bawol, R.; Goldberg, R.; Cassady, J.; Schiffman, J.; Feuer, William J; Gillings, D.

In: Ophthalmology, Vol. 94, No. 6, 06.08.1987, p. 620-629.

Research output: Contribution to journalArticle

Flynn, JT, Bancalari, E, Bachynski, BN, Buckley, EB, Bawol, R, Goldberg, R, Cassady, J, Schiffman, J, Feuer, WJ & Gillings, D 1987, 'Retinopathy of prematurity. Diagnosis, severity, and natural history', Ophthalmology, vol. 94, no. 6, pp. 620-629.
Flynn JT, Bancalari E, Bachynski BN, Buckley EB, Bawol R, Goldberg R et al. Retinopathy of prematurity. Diagnosis, severity, and natural history. Ophthalmology. 1987 Aug 6;94(6):620-629.
Flynn, J. T. ; Bancalari, Eduardo ; Bachynski, B. N. ; Buckley, E. B. ; Bawol, R. ; Goldberg, R. ; Cassady, J. ; Schiffman, J. ; Feuer, William J ; Gillings, D. / Retinopathy of prematurity. Diagnosis, severity, and natural history. In: Ophthalmology. 1987 ; Vol. 94, No. 6. pp. 620-629.
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