Retinoblastoma Tumorigenesis

Michael A. Dyer, Michael A. Dyer, J. William Harbour, J. William Harbour, J. William Harbour

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Tumorigenesis is a multistep process that involves sequential genetic alterations [1]. Preneoplastic cells must overcome their dependence on extrinsic mitogenic signals, evade apoptosis, prevent degradation of life-span-limiting telomeres, recruit vasculature, and acquire invasive properties to become malignant tumor cells [1].

Original languageEnglish (US)
Title of host publicationClinical Ophthalmic Oncology: Retinoblastoma, Second Edition
PublisherSpringer Berlin Heidelberg
Pages61-68
Number of pages8
ISBN (Print)9783662434512, 9783662434505
DOIs
StatePublished - Jan 1 2015

Fingerprint

Retinoblastoma
Carcinogenesis
Telomere
Apoptosis
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Dyer, M. A., Dyer, M. A., William Harbour, J., Harbour, J. W., & Harbour, J. W. (2015). Retinoblastoma Tumorigenesis. In Clinical Ophthalmic Oncology: Retinoblastoma, Second Edition (pp. 61-68). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-662-43451-2_6

Retinoblastoma Tumorigenesis. / Dyer, Michael A.; Dyer, Michael A.; William Harbour, J.; Harbour, J. William; Harbour, J. William.

Clinical Ophthalmic Oncology: Retinoblastoma, Second Edition. Springer Berlin Heidelberg, 2015. p. 61-68.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dyer, MA, Dyer, MA, William Harbour, J, Harbour, JW & Harbour, JW 2015, Retinoblastoma Tumorigenesis. in Clinical Ophthalmic Oncology: Retinoblastoma, Second Edition. Springer Berlin Heidelberg, pp. 61-68. https://doi.org/10.1007/978-3-662-43451-2_6
Dyer MA, Dyer MA, William Harbour J, Harbour JW, Harbour JW. Retinoblastoma Tumorigenesis. In Clinical Ophthalmic Oncology: Retinoblastoma, Second Edition. Springer Berlin Heidelberg. 2015. p. 61-68 https://doi.org/10.1007/978-3-662-43451-2_6
Dyer, Michael A. ; Dyer, Michael A. ; William Harbour, J. ; Harbour, J. William ; Harbour, J. William. / Retinoblastoma Tumorigenesis. Clinical Ophthalmic Oncology: Retinoblastoma, Second Edition. Springer Berlin Heidelberg, 2015. pp. 61-68
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