Retinal pigment epithelium function in alopecia areata

Antonella Tosti, Stefano Colombati, Maria Pia De Padova, Simonetta Guidelli Guidi, Giovanni Tosti, Enrico Maccolini

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Electroretinography (ERG) and electro-oculography (EOG) were performed in 98 patients affected by alopecia areata (AA) free from ophthalmologic disorders, and in 40 healthy subjects, in order to evaluate whether or not the retinal pigment epithelium of AA patients shows bioelectrical changes. ERG was normal. EOG, on the contrary, showed a significantly depressed mean value in the AA patient group. Furthermore, depressed EOG occurred more frequently in patients affected by alopecia totalis or universalis as compared with multiple patchy alopecia. These findings prompt the authors to believe that the melanocytes may play a prominent part in the pathogenesis of AA.

Original languageEnglish
Pages (from-to)553-555
Number of pages3
JournalJournal of Investigative Dermatology
Volume86
Issue number5
StatePublished - May 1 1986
Externally publishedYes

Fingerprint

Alopecia Areata
Retinal Pigments
Retinal Pigment Epithelium
Electroretinography
Melanocytes
Alopecia
Healthy Volunteers

ASJC Scopus subject areas

  • Dermatology

Cite this

Tosti, A., Colombati, S., De Padova, M. P., Guidi, S. G., Tosti, G., & Maccolini, E. (1986). Retinal pigment epithelium function in alopecia areata. Journal of Investigative Dermatology, 86(5), 553-555.

Retinal pigment epithelium function in alopecia areata. / Tosti, Antonella; Colombati, Stefano; De Padova, Maria Pia; Guidi, Simonetta Guidelli; Tosti, Giovanni; Maccolini, Enrico.

In: Journal of Investigative Dermatology, Vol. 86, No. 5, 01.05.1986, p. 553-555.

Research output: Contribution to journalArticle

Tosti, A, Colombati, S, De Padova, MP, Guidi, SG, Tosti, G & Maccolini, E 1986, 'Retinal pigment epithelium function in alopecia areata', Journal of Investigative Dermatology, vol. 86, no. 5, pp. 553-555.
Tosti A, Colombati S, De Padova MP, Guidi SG, Tosti G, Maccolini E. Retinal pigment epithelium function in alopecia areata. Journal of Investigative Dermatology. 1986 May 1;86(5):553-555.
Tosti, Antonella ; Colombati, Stefano ; De Padova, Maria Pia ; Guidi, Simonetta Guidelli ; Tosti, Giovanni ; Maccolini, Enrico. / Retinal pigment epithelium function in alopecia areata. In: Journal of Investigative Dermatology. 1986 ; Vol. 86, No. 5. pp. 553-555.
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