Retinal pigment epithelium function in alopecia areata

Antonella Tosti, Stefano Colombati, Maria Pia De Padova, Simonetta Guidelli Guidi, Giovanni Tosti, Enrico Maccolini

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Electroretinography (ERG) and electro-oculography (EOG) were performed in 98 patients affected by alopecia areata (AA) free from ophthalmologic disorders, and in 40 healthy subjects, in order to evaluate whether or not the retinal pigment epithelium of AA patients shows bioelectrical changes. ERG was normal. EOG, on the contrary, showed a significantly depressed mean value in the AA patient group. Furthermore, depressed EOG occurred more frequently in patients affected by alopecia totalis or universalis as compared with multiple patchy alopecia. These findings prompt the authors to believe that the melanocytes may play a prominent part in the pathogenesis of AA.

Original languageEnglish (US)
Pages (from-to)553-555
Number of pages3
JournalJournal of Investigative Dermatology
Volume86
Issue number5
DOIs
StatePublished - May 1986
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology

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  • Cite this

    Tosti, A., Colombati, S., De Padova, M. P., Guidi, S. G., Tosti, G., & Maccolini, E. (1986). Retinal pigment epithelium function in alopecia areata. Journal of Investigative Dermatology, 86(5), 553-555. https://doi.org/10.1111/1523-1747.ep12355013