Retinal detachment after subretinal stem cell transplantation

Ella Leung, Harry W Flynn, Thomas A Albini, Carlos A. Medina

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A 60-year-old man with Stargardt's macular dystrophy and visual acuity of 20/400 in the right eye and 20/60 in the left eye underwent a subretinal injection of autologous bone marrow-derived stem cells in the right eye. The patient developed a retinal detachment in the right eye 2 months later that was initially treated with a scleral buckle, but the patient subsequently developed a recurrent retinal detachment with proliferative vitreoretinopathy. A pars plana vitrectomy, membrane peel, fluid-air exchange, endolaser, and silicone oil injection were then performed. The retina remained attached 5 months later, with improvement in visual acuity from hand motions to 20/300 post-vitrectomy. Retinal detachment may occur after subretinal injection of stem cells. Proliferative vitreoretinopathy may develop in these patients, but the visual acuity may return to baseline after retinal reattachment.

Original languageEnglish (US)
Pages (from-to)600-601
Number of pages2
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume47
Issue number6
DOIs
StatePublished - Jun 1 2016

Fingerprint

Stem Cell Transplantation
Retinal Detachment
Visual Acuity
Proliferative Vitreoretinopathy
Vitrectomy
Injections
Stem Cells
Patient Acuity
Silicone Oils
Temazepam
Macular Degeneration
Retina
Hand
Bone Marrow
Air
Membranes

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

Retinal detachment after subretinal stem cell transplantation. / Leung, Ella; Flynn, Harry W; Albini, Thomas A; Medina, Carlos A.

In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 47, No. 6, 01.06.2016, p. 600-601.

Research output: Contribution to journalArticle

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