Results of retroviral and adenoviral approaches to cancer gene therapy.

L. H. Yin, S. Q. Fu, T. Nanakorn, F. Garcia-Sanchez, I. Chung, R. Cote, G. Pizzorno, E. Hanania, S. Heimfeld, R. Crystal, A. Deisseroth

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations

Abstract

Genetic modification for cancer treatment has involved the introduction of chemotherapy protection and sensitization genes into normal and tumor cells, respectively, for the purpose of improving the outcome of conventional approaches to the treatment of solid tumor neoplasms. This paper will review the use of multidrug resistance-1 retroviral vectors and cytosine deaminase adenoviral prodrug activation vectors for this purpose.

Original languageEnglish (US)
Pages (from-to)247-250
Number of pages4
JournalStem cells (Dayton, Ohio)
Volume16 Suppl 1
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine
  • Developmental Biology
  • Cell Biology

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