Response properties of cells in the dorsal lateral geniculate nucleus of the albino rat

Kenneth V. Anderson, Vance Lemmon, Howard S. Rosing

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The response patterns of cells in the dorsal lateral geniculate nucleus of the albino rat were studied in order to examine the functional organization of the lateral geniculate nucleus. Both photic stimulation and electrical stimulation of the optic tract were used to activate single units in the lateral geniculate nuclei. Three different types of response patterns were found for principal cells, while interneurons all had similar response patterns. The first class of principal cells, E-S cells, responded to stimulation with a period of excitation, followed by a period when activity was suppressed. A second class of cells, S cells, responded to photic stimulation with an initial period when activity was suppressed. The final class of cells, E cells, responded with a period of excitation followed by a return to spontaneous rates of firing. The response patterns of E cells suggest that this type of principal neuron does not receive feedback inhibition of the type proposed in previous models of the lateral geniculate nuclei. Based on these and other observations, a new model of the functional organization of the lateral geniculate nuclei is proposed.

Original languageEnglish (US)
Pages (from-to)143-152
Number of pages10
JournalJournal of Neuroscience Research
Volume3
Issue number2
DOIs
StatePublished - 1977
Externally publishedYes

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Keywords

  • central nervous system
  • lateral geniculate
  • neurophysiology
  • vision
  • visual anatomical model
  • visual response types

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience

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