Response of retinal vasculature to phenylephrine

G. Ferrari-Dileo, E. B. Davis, D. R. Anderson

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


In a freshly enucleated bovine eye, the retinal arteries and veins constrict when phenylephrine is applied directly on the surface of the vessel walls. This 'in situ' preparation allowed us to observe the reaction of retinal vessels without any surgical procedure that might alter the vascular response to agonists. These results indicate that alpha1-adrenergic receptors are present in the retinal vessels, which might therefore respond to vasoactive hormones. If, when, and how these reactions occur is still to be studied.

Original languageEnglish (US)
Pages (from-to)1181-1182
Number of pages2
JournalInvestigative Ophthalmology and Visual Science
Issue number6
StatePublished - 1990


  • alpha-adrenergic receptors
  • bovine eye
  • contractions
  • phenylephrine
  • retinal blood vessels

ASJC Scopus subject areas

  • Ophthalmology


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