Resolution of vulvitis circumscripta plasmacellularis with topical imiquimod: Two case reports

H. L. Ee, G. Yosipovitch, R. Chan, B. H. Ong, Melvin Ee

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Vulvitis circumscripta plasmacellularis (VCP) is a rare but well-described entity. It is notorious for its recalcitrant nature to various modalities of treatment. Intralesional interferon-α showed some promise, with complete resolution, but is coupled with the side-effect of myelosuppression. Topical imiquimod is a novel immune response modifier with the ability to induce the production of interferon-α. In this paper, we report two cases of VCP whose lesions were resistant to antibiotics, topical and oral corticosteroids, but resolved after a treatment trial with imiquimod.

Original languageEnglish (US)
Pages (from-to)638-641
Number of pages4
JournalBritish Journal of Dermatology
Volume149
Issue number3
DOIs
StatePublished - Sep 1 2003
Externally publishedYes

Keywords

  • Imiquimod
  • Vulvitis circumscripta plasmacellularis
  • Zoon's vulvitis

ASJC Scopus subject areas

  • Dermatology

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