Renal volumetric analysis: A new paradigm in renal mass treatment assessment

Vladislav Gorbatiy, Viacheslav Iremashvili, Arturo Castro, Amanda Mure, Nicolas Ortiz, Scott M. Castle, Raymond J. Leveillee

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background and Purpose: Multiple renal volumetric assessment studies have correlated parenchymal volume with the glomerular filtration rate. The objective of this study was to compare renal volumes before and after treatment of renal masses with either partial nephrectomy or radiofrequency ablation (RFA). Patients and Methods: We reviewed our prospectively collected database of patients with renal masses who were treated between November 2001 and January 2011 with robot-assisted laparoscopic partial nephrectomy (RALPN), laparoscopic RFA (LRFA), or CT-guided percutaneous RFA (CTRFA). Digital Imaging and Communications in Medicine CT imaging data were analyzed in an open-source viewer. Volumetric calculations were used to measure the normal, enhancing bilateral renal parenchyma and tumor volumes. Normal parenchymal volume loss was compared among treatments. Results: There were 96 patients (68 men) with an average age of 68.0 (36-84) years who met our inclusion criteria. The average tumor diameter, tumor volume, and nephrometry score (NS) was 3.5 cm, 32.0 cm3, and 7.1 in RALPN (n=26), 2.6 cm, 9.8 cm3, and 7.1 in CTRFA (n=47), and 2.9 cm, 14.3 cm3, and 7.2 in LRFA (n=23) groups. The percent change in the operated kidney volume was similar in RALPN (-12%±15), CTRFA (-13%±16), and LRFA (-17%±18) groups. NS was the only variable in a multivariate linear regression model that correlated with the amount of volume lost in the ipsilateral kidney. Conclusions: Our retrospective volumetric analysis of renal parenchyma before and after partial nephrectomy or RFA of renal masses revealed that all treatments produce similar volume of collateral damage.

Original languageEnglish
Pages (from-to)361-365
Number of pages5
JournalJournal of Endourology
Volume27
Issue number3
DOIs
StatePublished - Mar 1 2013
Externally publishedYes

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Kidney
Nephrectomy
Therapeutics
Tumor Burden
Linear Models
Glomerular Filtration Rate
Communication
Medicine
Databases
Neoplasms

ASJC Scopus subject areas

  • Urology

Cite this

Gorbatiy, V., Iremashvili, V., Castro, A., Mure, A., Ortiz, N., Castle, S. M., & Leveillee, R. J. (2013). Renal volumetric analysis: A new paradigm in renal mass treatment assessment. Journal of Endourology, 27(3), 361-365. https://doi.org/10.1089/end.2012.0195

Renal volumetric analysis : A new paradigm in renal mass treatment assessment. / Gorbatiy, Vladislav; Iremashvili, Viacheslav; Castro, Arturo; Mure, Amanda; Ortiz, Nicolas; Castle, Scott M.; Leveillee, Raymond J.

In: Journal of Endourology, Vol. 27, No. 3, 01.03.2013, p. 361-365.

Research output: Contribution to journalArticle

Gorbatiy, V, Iremashvili, V, Castro, A, Mure, A, Ortiz, N, Castle, SM & Leveillee, RJ 2013, 'Renal volumetric analysis: A new paradigm in renal mass treatment assessment', Journal of Endourology, vol. 27, no. 3, pp. 361-365. https://doi.org/10.1089/end.2012.0195
Gorbatiy V, Iremashvili V, Castro A, Mure A, Ortiz N, Castle SM et al. Renal volumetric analysis: A new paradigm in renal mass treatment assessment. Journal of Endourology. 2013 Mar 1;27(3):361-365. https://doi.org/10.1089/end.2012.0195
Gorbatiy, Vladislav ; Iremashvili, Viacheslav ; Castro, Arturo ; Mure, Amanda ; Ortiz, Nicolas ; Castle, Scott M. ; Leveillee, Raymond J. / Renal volumetric analysis : A new paradigm in renal mass treatment assessment. In: Journal of Endourology. 2013 ; Vol. 27, No. 3. pp. 361-365.
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