Renal subcapsular xenotransplantation of purified porcine islets

Camillo Ricordi; Paul E. Lacy

doi:10.1097/00007890-198711000-00026

Renal subcapsular xenotransplantation of purified porcine islets

Camillo Ricordi, Paul E. Lacy

Research output: Contribution to journal › Comment/debate › peer-review

26 Scopus citations

Abstract

In this study, purified porcine islets were separated from the adult pig pancreas using a previously described method, and transplanted beneath the renal capsule of nude mice. The results suggest that porcine islets are well preserved and morphologically intact in all the recipients one month after transplantation. The functional integrity was also confirmed in two nude mice with streptozotocin-induced diabetes.

Original language	English (US)
Pages (from-to)	721-723
Number of pages	3
Journal	Transplantation
Volume	44
Issue number	5
DOIs	https://doi.org/10.1097/00007890-198711000-00026
State	Published - Nov 1987
Externally published	Yes

ASJC Scopus subject areas

Transplantation

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title = "Renal subcapsular xenotransplantation of purified porcine islets",

abstract = "In this study, purified porcine islets were separated from the adult pig pancreas using a previously described method, and transplanted beneath the renal capsule of nude mice. The results suggest that porcine islets are well preserved and morphologically intact in all the recipients one month after transplantation. The functional integrity was also confirmed in two nude mice with streptozotocin-induced diabetes.",

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AB - In this study, purified porcine islets were separated from the adult pig pancreas using a previously described method, and transplanted beneath the renal capsule of nude mice. The results suggest that porcine islets are well preserved and morphologically intact in all the recipients one month after transplantation. The functional integrity was also confirmed in two nude mice with streptozotocin-induced diabetes.

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