Renal regulation of acid-base balance in a freshwater fish (1).

C. M. Wood, F. H. Caldwell

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Intra-arterial injection of a fixed acid load caused only a short-lived (less than 2h) disturbance of blood pH but a long lived (2-3 days) elevation of urinary acid excretion in freshwater trout (Salmo gairdneri). The renal response comprised an immediate increase in acid output in the form of titratable acidity minus bicarbonate, and a slower rise in acid output in the form of ammonia. The total elevation in urinary acid efflux over 72h was such that no other mechanism besides renal function is needed to explain the ultimate compensation of this experimental acid-base disturbance.

Original languageEnglish
Pages (from-to)301-307
Number of pages7
JournalJournal of Experimental Zoology
Issue number2
StatePublished - Aug 1 1978


ASJC Scopus subject areas

  • Animal Science and Zoology

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