Renal parenchymal hypertension: Current concepts of pathogenesis and management

Richard A. Preston, Irwin Singer, Murray Epstein

Research output: Contribution to journalReview articlepeer-review

39 Scopus citations


Renal parenchymal disease is a common but often unrecognized cause of hypertension. Chronic renal disease and systemic hypertension may coexist in two distinct settings. First, essential hypertension is an important cause of chronic renal disease. Second, renal parenchymal disease is a well-established cause of secondary hypertension. Renal parenchymal disease is the most common cause of secondary hypertension, accounting for 2.5% to 5.0% of all cases of systemic hypertension.1 Secondary hypertension may also accelerate the decline in renal function if inadequately controlled.1-9 Therefore, hypertension is both a cause and a consequence of renal disease, and it may be difficult to distinguish them clinically.

Original languageEnglish (US)
Pages (from-to)602-611
Number of pages10
JournalArchives of internal medicine
Issue number6
StatePublished - Mar 25 1996
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine


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