Renal mucormycosis in the HIV patient.

J. A. Guardia, J. Bourgoignie, J. Diego

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Mucormycosis is an increasingly recognized opportunistic infection. It usually affects patients with debilitating conditions such as cancer, diabetes mellitus, renal failure, and extensive burns. Mucor infection has also been described in human immunodeficiency virus (HIV) patients. The most common clinical presentations are the cerebral, cutaneous, and renal forms. We describe a unique case of bilateral renal mucormycosis presenting with renal failure in an HIV-infected patient. In the immunosuppressed host, a history of intravenous (IV) drug abuse associated with symptoms of pyelonephritis should alert the clinician to the possibility of mucor infection. Blood and urine culture are often negative. The diagnosis is made histologically in most cases. The treatment of HIV patients with mucormycosis and renal failure includes hemodialysis, nephrectomy, and intravenous amphotericin in addition to antiretroviral therapy. Bilateral renal involvement with Mucor carries a poor prognosis.

Original languageEnglish (US)
Pages (from-to)E24
JournalAmerican journal of kidney diseases : the official journal of the National Kidney Foundation
Volume35
Issue number5
StatePublished - May 2000

ASJC Scopus subject areas

  • Nephrology

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