Remission of relapsing childhood nephrotic syndrome with mycophenolate mofetil

Manju Chandra, Myron Susin, Carolyn Abitbol

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

We report a 21-year-old male with childhood onset familial nephrotic syndrome and frequent relapses who manifested toxicity or treatment resistance to corticosteroids, cyclophosphamide, cyclosporin-A, and tacrolimus. Monotherapy with mycophenolate mofetil (MMF) resulted in maintenance of clinical remission for 14 months without noticeable toxicity, while allowing resolution of steroid-induced side effects. Our observation suggests that MMF may be useful in maintaining remission in nephrotic patients who manifest toxicity to standard immunosuppressive agents.

Original languageEnglish
Pages (from-to)224-226
Number of pages3
JournalPediatric Nephrology
Volume14
Issue number3
StatePublished - Mar 1 2000

    Fingerprint

Keywords

  • Focal segmental glomerulosclerosis
  • Idiopathic nephrotic syndrome
  • Minimal change disease
  • Mycophenolate mofetil

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Cite this