Reliability of immunofluorescence of renal tissue obtained at autopsy

K. Sheibani, R. R. Tubbs, R. Valenzuela, S. Deodhar

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A retrospective study of kidney tissues accessioned in the Department of Immunopathology was undertaken to determine the reliability of the direct immunofluorescence technic applied to necropsy tissues. Of 72 accessioned specimens, 27 were positive and showed a spectrum of immunomicroscopic patterns corresponding to different renal diseases. Only two patients whose specimens were negative by immunofluorescence had shown any clinical or light microscopic evidence of active glomerular disease. Periods from death to auropsy ranged from one to 20 hours. Positive fluorescence was found in tissues obtained as long as 20 hours after death. These findings suggest that immunofluorescent studies of autopsy-derived renal tissue yield acceptable results.

Original languageEnglish (US)
Pages (from-to)222-224
Number of pages3
JournalAmerican journal of clinical pathology
Issue number2
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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