Reliability and validity of the Cystic Fibrosis Questionnaire-Revised for children and parents in Turkey: Cross-sectional study

Hasan Yuksel, Ozge Yilmaz, Deniz Dogru, Bulent Karadag, Fatih Unal, Alexandra L. Quittner

Research output: Contribution to journalArticle

3 Scopus citations


Purpose: The purpose of study was to translate Cystic Fibrosis Questionnaire-Revised (CFQ-R) into Turkish for children with cystic fibrosis (CF) and evaluate its reliability and validity. This is the first CF-specific health-related quality of life (HRQOL) measure validated in a Muslim country. Methods: Fifty-one children aged 6-13 years treated at four centers in Turkey and 30 parents participated in this cross-sectional study. Demographic characteristics and disease severity parameters were recorded for all participants. All participants completed the parent or child versions of CFQ-R and KINDL questionnaires at enrollment. Reliability and construct validity analysis were carried out. Results: Both children and parents endorsed a range of responses, with no evidence of floor or ceiling effects. Item-to-total correlations indicated that most items were more highly correlated with their intended scale than competing scales. Good internal consistency was found for majority of child and parent scales. CFQ-R scales correlated significantly with clinical indices of disease severity. Good evidence of convergent validity with a generic HRQOL scale was found. Conclusion: Turkish versions of CFQ-R Child and Parent instruments have demonstrated adequate reliability and validity and can be utilized in clinical trials or integrated into clinical evaluation and follow-up of Turkish children with CF.

Original languageEnglish (US)
Pages (from-to)409-414
Number of pages6
JournalQuality of Life Research
Issue number2
StatePublished - Mar 1 2013



  • Cystic fibrosis
  • Cystic Fibrosis Questionnaire-Revised
  • Reliability
  • Validity

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Medicine(all)

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