Release and Synthesis of Luteinizing Hormone and Follicle-Stimulating Hormone in Pituitary Cultures in Response to Hypothalamic Preparations (34681)

James C. Mittler, Akira Arimura, Andrew V. Schally

Research output: Contribution to journalArticle

26 Scopus citations


Addition of microgram amounts of highly purified porcine LH-RH twice daily for 3 days to female rat anterior pituitaries in vitro significantly increased the quantities of LH and FSH released. Total LH and FSH contents in stimulated tissue and medium exceeded those of controls as measured by radioimmunoassays for LH and FSH and by bioassay for FSH.

Original languageEnglish (US)
Pages (from-to)1321-1325
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number4
StatePublished - Apr 1970
Externally publishedYes


ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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