Abstract
We describe a 33-year-old homosexual man with a steroid-responsive, remitting and relapsing leukoencephalopathy associated with recent human immunodeficiency virus type 1 (HIV-1) seroconversion. Biopsy of a parieto-occipital lesion revealed demyelination and astrogliosis with focal necrosis. Detailed investigations demonstrated no pathogens in the brain other than HIV-1. This patient illustrates that a neurological disorder clinically indistinguishable from multiple sclerosis may be the presenting manifestation of HIV-1 infection and may occur in the absence of clinically significant immunosuppression.
Original language | English (US) |
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Pages (from-to) | 34-38 |
Number of pages | 5 |
Journal | Annals of neurology |
Volume | 31 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1992 |
ASJC Scopus subject areas
- Neurology
- Clinical Neurology