Relapses in the Guillain-Barre syndrome after treatment with intravenous immune globulin or plasma exchange

J. G. Romano, F. T. Rotta, P. Potter, V. Rosenfeld, R. Santibanez, B. Rocha, W. G. Bradley

Research output: Contribution to journalArticle

18 Scopus citations


To clarify the question of whether Guillain-Barre syndrome (GBS) patients treated with intravenous immune globulin (IVIG) relapse at a higher frequency than those treated with plasma exchange (PE), 54 patients with GBS were studied retrospectively. A higher frequency of relapses was noted in the PE-treated patients than in those receiving IVIG. The presence of an associated medical condition correlated with an increased risk of relapses, while earlier onset of treatment resulted in a decrease of relapses of GBS. This study found no support for prior suggestions of increased relapses in patients with GBS treated with IVIG as opposed to those treated with PE.

Original languageEnglish (US)
Pages (from-to)1327-1330
Number of pages4
JournalMuscle and Nerve
Issue number10
StatePublished - Sep 12 1998



  • Guillain-Barre syndrome
  • Intravenous immune globulin
  • Plasma exchange
  • Relapses

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

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