Rehabilitation of motor dysfunction in primary brain tumor patients

David S. Kushner, Christina Amidei

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


In 2010 it was estimated that .688 000 Americans were living with a primary brain tumor (PBT) corresponding to a U.S. prevalence rate of approximately 221.8 per 100 000 people. Five-year survival is 96.1% in nonmalignant PBTs, 34% in malignant PBTs for all ages, and 71% in children [1985-2005]. Case fatality rates have decreased in the U.S. since the 1970's for nonmalignant PBTs and for medulloblastoma, oligodendroglioma, and astrocytoma. Statistics of increasing survival highlight the importance of rehabilitation interventions to improve function and quality of life in survivors. PBT motor dysfunction is multifactorial, occurring as a result of direct effects of tumor and/or swelling or as a result of treatments; etiologies include encephalopathy, myopathy, neuropathy, infection, poor nutrition, metabolic factors, emotional factors, impaired perception/vision/cognition and complications of immobility. Motor dysfunction may lead to: impaired mobility, impaired activities of daily living, risk for complications of immobility, falls, pain, anxiety/ depression, and loss of functional independence and quality of life. Rehabilitation treatment strategies target specific causes of motor dysfunction to improve functional independence and quality of life. This article reviews current knowledge and controversy regarding the role of rehabilitation for motor disorders in PBT patients.

Original languageEnglish (US)
Article numbernpv019
Pages (from-to)185-191
Number of pages7
JournalNeuro-Oncology Practice
Issue number4
StatePublished - Feb 26 2015


  • Brain tumors
  • Motor skills disorders
  • Quality of life
  • Rehabilitation
  • Survival

ASJC Scopus subject areas

  • Medicine (miscellaneous)


Dive into the research topics of 'Rehabilitation of motor dysfunction in primary brain tumor patients'. Together they form a unique fingerprint.

Cite this