1. 1. The effects of anemia and hypoxia on erythropoiesis in Lepisosteus platyrhincus were examined. 2. 2. Following bleeding, cells morphologically similar to erythroblasts appeared in the circulation and their appearance was paralleled by increases in [14C]δ-aminolevulinic acid and 3H-thymidine uptake by peripheral blood cells. 3. 3. The appearance of heme synthesizing erythroid cells in the circulation could be blocked if the anemia was corrected within 24 hr from bleeding, but not if corrected after 48 hr. 4. 4. Erythropoiesis was not stimulated by hypoxic hypoxia, exposure to carbon monoxide or by drugs that are known to stimulate erythropoiesis in mammals. 5. 5. Alteration of the plasma volume without decreasing red cell mass did not stimulate erythropoiesis.
|Original language||English (US)|
|Number of pages||6|
|Journal||Comparative Biochemistry and Physiology -- Part A: Physiology|
|State||Published - 1978|
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