Abstract
We tested whether a regular exercise regimen was associated with a change in the life span of G93A-SOD1 transgenic mice, a model of familial ALS. Regular treadmill running for 10 weeks led to a significant increase in the life span of G93A-SOD1 mice. The effect was stronger in male mice, whereas there was only a trend between exercised and sedentary female G93A-SOD1 mice. The data suggest that regular exercise has a beneficial effect on the progression of ALS.
Original language | English (US) |
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Pages (from-to) | 804-807 |
Number of pages | 4 |
Journal | Annals of neurology |
Volume | 53 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2003 |
ASJC Scopus subject areas
- Neurology
- Clinical Neurology