Regional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19

A. Mitchell, A. E. Bale, B. J. Lee, D. Hatfield, H. Harley, S. A. Rundle, Yao-Shan Fan, Y. Fukushima, T. B. Shows, O. W. McBride

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The human selenocysteine tRNA gene (TRSP) has been localized on chromosome 19q13.2 → q13.3 by in situ hybridization and ordered with respect to other genes and anonymous DNA markers in this region by linkage analysis in the forty CEPH pedigrees. These loci span only 10 cM in males and about 30 cM in females. The order of the loci is cen... D19S7-D19S9-D19S47-CYP2A-CYP2F1-APOC2-(TRSP, CKM). CYP2B flanks the CYP2A and CYP2F1 loci, but it cannot be determined whether it is proximal or distal to the other two cytochrome P450 loci with respect to the centromere.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalCytogenetics and Cell Genetics
Volume61
Issue number2
StatePublished - Jan 1 1992
Externally publishedYes

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Chromosomes, Human, Pair 19
Human Chromosomes
Centromere
Pedigree
Genetic Markers
Cytochrome P-450 Enzyme System
Genes
In Situ Hybridization
Chromosomes
steroid hormone 7-alpha-hydroxylase
selenocysteinyl-tRNA

ASJC Scopus subject areas

  • Cell Biology
  • Genetics

Cite this

Mitchell, A., Bale, A. E., Lee, B. J., Hatfield, D., Harley, H., Rundle, S. A., ... McBride, O. W. (1992). Regional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19. Cytogenetics and Cell Genetics, 61(2), 117-120.

Regional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19. / Mitchell, A.; Bale, A. E.; Lee, B. J.; Hatfield, D.; Harley, H.; Rundle, S. A.; Fan, Yao-Shan; Fukushima, Y.; Shows, T. B.; McBride, O. W.

In: Cytogenetics and Cell Genetics, Vol. 61, No. 2, 01.01.1992, p. 117-120.

Research output: Contribution to journalArticle

Mitchell, A, Bale, AE, Lee, BJ, Hatfield, D, Harley, H, Rundle, SA, Fan, Y-S, Fukushima, Y, Shows, TB & McBride, OW 1992, 'Regional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19', Cytogenetics and Cell Genetics, vol. 61, no. 2, pp. 117-120.
Mitchell A, Bale AE, Lee BJ, Hatfield D, Harley H, Rundle SA et al. Regional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19. Cytogenetics and Cell Genetics. 1992 Jan 1;61(2):117-120.
Mitchell, A. ; Bale, A. E. ; Lee, B. J. ; Hatfield, D. ; Harley, H. ; Rundle, S. A. ; Fan, Yao-Shan ; Fukushima, Y. ; Shows, T. B. ; McBride, O. W. / Regional localization of the selenocysteine tRNA gene (TRSP) on human chromosome 19. In: Cytogenetics and Cell Genetics. 1992 ; Vol. 61, No. 2. pp. 117-120.
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AU - Harley, H.

AU - Rundle, S. A.

AU - Fan, Yao-Shan

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AU - Shows, T. B.

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