Regenerative medicine for the urethra

Tamer Aboushwareb, Anthony Atala, Abdelwahab Elkassaby

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Replacement of damaged or diseased tissues represents one of the most challenging aspects of medicine. Within the urinary tract, tissue replacement is a technically demanding procedure. In particular, urethral reconstruction has posed a continuing challenge to the reconstructive urologist. Various surgical techniques utilizing flaps or grafts (genital/extragenital), whether single or multistage, have been used for urethral reconstruction with satisfactory results. Genital skin, however, is not always readily available and most graft harvesting procedures are technically demanding and time consuming. The development of an 'off-the-shelf' graft material may be the answer to this old urological dilemma. In this chapter, we review the current materials, whether synthetic or natural, that have been used in clinical or preclinical studies for the purpose of urethral reconstruction.

Original languageEnglish (US)
Title of host publicationBiomaterials and Tissue Engineering in Urology
PublisherElsevier Ltd
Pages454-469
Number of pages16
ISBN (Print)9781845694029
DOIs
StatePublished - Apr 2009

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ASJC Scopus subject areas

  • Dentistry(all)
  • Medicine(all)

Cite this

Aboushwareb, T., Atala, A., & Elkassaby, A. (2009). Regenerative medicine for the urethra. In Biomaterials and Tissue Engineering in Urology (pp. 454-469). Elsevier Ltd. https://doi.org/10.1533/9781845696375.3.454