Abstract
Cytoplasmic acidification in taste receptor cells is thought to be involved, at least in part, in acid taste transduction. Since in taste buds about 20% of the receptor cells are electrically coupled, we have tested whether reduction in intracellular pH affects these lateral synaptic interactions. By applying the patch clamp technique to a slice preparation of Necturus lingual epithelium, we found that electrical coupling between taste receptor cells was strongly reduced by cytoplasmic acidification. Therefore, electrical coupling in taste buds might be modified during acid stimulation.
| Original language | English |
|---|---|
| Pages (from-to) | 212-216 |
| Number of pages | 5 |
| Journal | Neuroscience Letters |
| Volume | 176 |
| Issue number | 2 |
| DOIs | |
| State | Published - Aug 1 1994 |
| Externally published | Yes |
Fingerprint
Keywords
- Acid transduction
- Electrical coupling
- Gustation
- Intracellular pH
- Necturus
- Patch-clamp
- Taste bud
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Reduction of electrical coupling between Necturus taste receptor cells, a possible role in acid taste. / Bigiani, Albertino; Roper, Stephen D.
In: Neuroscience Letters, Vol. 176, No. 2, 01.08.1994, p. 212-216.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Reduction of electrical coupling between Necturus taste receptor cells, a possible role in acid taste
AU - Bigiani, Albertino
AU - Roper, Stephen D
PY - 1994/8/1
Y1 - 1994/8/1
N2 - Cytoplasmic acidification in taste receptor cells is thought to be involved, at least in part, in acid taste transduction. Since in taste buds about 20% of the receptor cells are electrically coupled, we have tested whether reduction in intracellular pH affects these lateral synaptic interactions. By applying the patch clamp technique to a slice preparation of Necturus lingual epithelium, we found that electrical coupling between taste receptor cells was strongly reduced by cytoplasmic acidification. Therefore, electrical coupling in taste buds might be modified during acid stimulation.
AB - Cytoplasmic acidification in taste receptor cells is thought to be involved, at least in part, in acid taste transduction. Since in taste buds about 20% of the receptor cells are electrically coupled, we have tested whether reduction in intracellular pH affects these lateral synaptic interactions. By applying the patch clamp technique to a slice preparation of Necturus lingual epithelium, we found that electrical coupling between taste receptor cells was strongly reduced by cytoplasmic acidification. Therefore, electrical coupling in taste buds might be modified during acid stimulation.
KW - Acid transduction
KW - Electrical coupling
KW - Gustation
KW - Intracellular pH
KW - Necturus
KW - Patch-clamp
KW - Taste bud
UR - http://www.scopus.com/inward/record.url?scp=0027931632&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027931632&partnerID=8YFLogxK
U2 - 10.1016/0304-3940(94)90085-X
DO - 10.1016/0304-3940(94)90085-X
M3 - Article
VL - 176
SP - 212
EP - 216
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 2
ER -