Reduction of electrical coupling between Necturus taste receptor cells, a possible role in acid taste

Albertino Bigiani, Stephen D Roper

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Cytoplasmic acidification in taste receptor cells is thought to be involved, at least in part, in acid taste transduction. Since in taste buds about 20% of the receptor cells are electrically coupled, we have tested whether reduction in intracellular pH affects these lateral synaptic interactions. By applying the patch clamp technique to a slice preparation of Necturus lingual epithelium, we found that electrical coupling between taste receptor cells was strongly reduced by cytoplasmic acidification. Therefore, electrical coupling in taste buds might be modified during acid stimulation.

Original languageEnglish
Pages (from-to)212-216
Number of pages5
JournalNeuroscience Letters
Volume176
Issue number2
DOIs
StatePublished - Aug 1 1994
Externally publishedYes

    Fingerprint

Keywords

  • Acid transduction
  • Electrical coupling
  • Gustation
  • Intracellular pH
  • Necturus
  • Patch-clamp
  • Taste bud

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this