Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome

Evangelos P. Misiakos, Antonio Pinna, Tomoaki Kato, Miguel G. Rodriguez, Antonio Francavilla, Vincenzo Mazzaferro, Phillip Ruiz, John D. Reith, Andreas G. Tzakis

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Background. Desmoid tumors are locally invasive fibromatous tumors, which, in patients with Gardner's syndrome, usually occur in the abdominal wall or intra-abdominally. After excision, they tend to recur, often leading to multiple bowel resections. Methods. This is a report of the clinical course of a patient with Gardner's syndrome and desmoid tumor who had multiple enterectomies and gradually developed short-gut syndrome. He required prolonged parenteral nutrition, which damaged the liver. The patient underwent a multivisceral transplantation as a life-saving procedure. Results. After the transplant, the desmoid tumor recurred in the thoracic wall twice and was successfully resected. It also recurred in the abdominal cavity, compressing the intestinal loops; the tumor was excised uneventfully, leaving the graft intact. The recurrent tumors were all of recipient origin. Conclusions. Intestinal and multivisceral transplantation could be considered in patients with short-gut syndrome caused by recurrent desmoid tumor. In the case of posttransplant tumor recurrence, resection is the only option recommended.

Original languageEnglish (US)
Pages (from-to)1197-1199
Number of pages3
Issue number8
StatePublished - Apr 27 1999

ASJC Scopus subject areas

  • Transplantation


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