Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome

Evangelos P. Misiakos, Antonio Pinna, Tomoaki Kato, Miguel G. Rodriguez, Antonio Francavilla, Vincenzo Mazzaferro, Phillip Ruiz, John D. Reith, Andreas G. Tzakis

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Background. Desmoid tumors are locally invasive fibromatous tumors, which, in patients with Gardner's syndrome, usually occur in the abdominal wall or intra-abdominally. After excision, they tend to recur, often leading to multiple bowel resections. Methods. This is a report of the clinical course of a patient with Gardner's syndrome and desmoid tumor who had multiple enterectomies and gradually developed short-gut syndrome. He required prolonged parenteral nutrition, which damaged the liver. The patient underwent a multivisceral transplantation as a life-saving procedure. Results. After the transplant, the desmoid tumor recurred in the thoracic wall twice and was successfully resected. It also recurred in the abdominal cavity, compressing the intestinal loops; the tumor was excised uneventfully, leaving the graft intact. The recurrent tumors were all of recipient origin. Conclusions. Intestinal and multivisceral transplantation could be considered in patients with short-gut syndrome caused by recurrent desmoid tumor. In the case of posttransplant tumor recurrence, resection is the only option recommended.

Original languageEnglish
Pages (from-to)1197-1199
Number of pages3
JournalTransplantation
Volume67
Issue number8
DOIs
StatePublished - Apr 27 1999

Fingerprint

Gardner Syndrome
Aggressive Fibromatosis
Transplants
Recurrence
Neoplasms
Transplantation
Abdominal Cavity
Parenteral Nutrition
Abdominal Wall
Thoracic Wall

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Misiakos, E. P., Pinna, A., Kato, T., Rodriguez, M. G., Francavilla, A., Mazzaferro, V., ... Tzakis, A. G. (1999). Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome. Transplantation, 67(8), 1197-1199. https://doi.org/10.1097/00007890-199904270-00021

Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome. / Misiakos, Evangelos P.; Pinna, Antonio; Kato, Tomoaki; Rodriguez, Miguel G.; Francavilla, Antonio; Mazzaferro, Vincenzo; Ruiz, Phillip; Reith, John D.; Tzakis, Andreas G.

In: Transplantation, Vol. 67, No. 8, 27.04.1999, p. 1197-1199.

Research output: Contribution to journalArticle

Misiakos, EP, Pinna, A, Kato, T, Rodriguez, MG, Francavilla, A, Mazzaferro, V, Ruiz, P, Reith, JD & Tzakis, AG 1999, 'Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome', Transplantation, vol. 67, no. 8, pp. 1197-1199. https://doi.org/10.1097/00007890-199904270-00021
Misiakos EP, Pinna A, Kato T, Rodriguez MG, Francavilla A, Mazzaferro V et al. Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome. Transplantation. 1999 Apr 27;67(8):1197-1199. https://doi.org/10.1097/00007890-199904270-00021
Misiakos, Evangelos P. ; Pinna, Antonio ; Kato, Tomoaki ; Rodriguez, Miguel G. ; Francavilla, Antonio ; Mazzaferro, Vincenzo ; Ruiz, Phillip ; Reith, John D. ; Tzakis, Andreas G. / Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome. In: Transplantation. 1999 ; Vol. 67, No. 8. pp. 1197-1199.
@article{399a3d7d81754409b2631f411441b60e,
title = "Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome",
abstract = "Background. Desmoid tumors are locally invasive fibromatous tumors, which, in patients with Gardner's syndrome, usually occur in the abdominal wall or intra-abdominally. After excision, they tend to recur, often leading to multiple bowel resections. Methods. This is a report of the clinical course of a patient with Gardner's syndrome and desmoid tumor who had multiple enterectomies and gradually developed short-gut syndrome. He required prolonged parenteral nutrition, which damaged the liver. The patient underwent a multivisceral transplantation as a life-saving procedure. Results. After the transplant, the desmoid tumor recurred in the thoracic wall twice and was successfully resected. It also recurred in the abdominal cavity, compressing the intestinal loops; the tumor was excised uneventfully, leaving the graft intact. The recurrent tumors were all of recipient origin. Conclusions. Intestinal and multivisceral transplantation could be considered in patients with short-gut syndrome caused by recurrent desmoid tumor. In the case of posttransplant tumor recurrence, resection is the only option recommended.",
author = "Misiakos, {Evangelos P.} and Antonio Pinna and Tomoaki Kato and Rodriguez, {Miguel G.} and Antonio Francavilla and Vincenzo Mazzaferro and Phillip Ruiz and Reith, {John D.} and Tzakis, {Andreas G.}",
year = "1999",
month = "4",
day = "27",
doi = "10.1097/00007890-199904270-00021",
language = "English",
volume = "67",
pages = "1197--1199",
journal = "Transplantation",
issn = "0041-1337",
publisher = "Lippincott Williams and Wilkins",
number = "8",

}

TY - JOUR

T1 - Recurrence of desmoid tumor in a multivisceral transplant patient with Gardner's syndrome

AU - Misiakos, Evangelos P.

AU - Pinna, Antonio

AU - Kato, Tomoaki

AU - Rodriguez, Miguel G.

AU - Francavilla, Antonio

AU - Mazzaferro, Vincenzo

AU - Ruiz, Phillip

AU - Reith, John D.

AU - Tzakis, Andreas G.

PY - 1999/4/27

Y1 - 1999/4/27

N2 - Background. Desmoid tumors are locally invasive fibromatous tumors, which, in patients with Gardner's syndrome, usually occur in the abdominal wall or intra-abdominally. After excision, they tend to recur, often leading to multiple bowel resections. Methods. This is a report of the clinical course of a patient with Gardner's syndrome and desmoid tumor who had multiple enterectomies and gradually developed short-gut syndrome. He required prolonged parenteral nutrition, which damaged the liver. The patient underwent a multivisceral transplantation as a life-saving procedure. Results. After the transplant, the desmoid tumor recurred in the thoracic wall twice and was successfully resected. It also recurred in the abdominal cavity, compressing the intestinal loops; the tumor was excised uneventfully, leaving the graft intact. The recurrent tumors were all of recipient origin. Conclusions. Intestinal and multivisceral transplantation could be considered in patients with short-gut syndrome caused by recurrent desmoid tumor. In the case of posttransplant tumor recurrence, resection is the only option recommended.

AB - Background. Desmoid tumors are locally invasive fibromatous tumors, which, in patients with Gardner's syndrome, usually occur in the abdominal wall or intra-abdominally. After excision, they tend to recur, often leading to multiple bowel resections. Methods. This is a report of the clinical course of a patient with Gardner's syndrome and desmoid tumor who had multiple enterectomies and gradually developed short-gut syndrome. He required prolonged parenteral nutrition, which damaged the liver. The patient underwent a multivisceral transplantation as a life-saving procedure. Results. After the transplant, the desmoid tumor recurred in the thoracic wall twice and was successfully resected. It also recurred in the abdominal cavity, compressing the intestinal loops; the tumor was excised uneventfully, leaving the graft intact. The recurrent tumors were all of recipient origin. Conclusions. Intestinal and multivisceral transplantation could be considered in patients with short-gut syndrome caused by recurrent desmoid tumor. In the case of posttransplant tumor recurrence, resection is the only option recommended.

UR - http://www.scopus.com/inward/record.url?scp=0033609166&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033609166&partnerID=8YFLogxK

U2 - 10.1097/00007890-199904270-00021

DO - 10.1097/00007890-199904270-00021

M3 - Article

VL - 67

SP - 1197

EP - 1199

JO - Transplantation

JF - Transplantation

SN - 0041-1337

IS - 8

ER -