Rectal misoprostol vs 15-methyl prostaglandin F for retained placenta after second-trimester delivery

Subha Sundaram, John P Diaz, Víctor Hugo González-Quintero, Usha Verma

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Objective: The purpose of this study was to compare rectal misoprostol (RM) with 15-methyl prostaglandin F2α (PGF) for the management of retained placenta after second-trimester deliveries. Study Design: A retrospective study of all second-trimester deliveries between the years 2000 and 2005 was performed. Women were divided into 2 groups, depending on whether they received RM or PGF after the delivery. Results: Three hundred three second-trimester deliveries were analyzed. The time from the administration of medications to the placental delivery was significantly shorter in women who received PGF, compared with the RM group (49.5 vs 89 minutes; P < .01). Women who received PGF had lower rates of retained placenta (4.9% vs 12.4%; P = .02). Conclusion: The use of PGF after second-trimester deliveries results in shorter third stage of labor and lower rates of retained placenta compared with RM.

Original languageEnglish (US)
Pages (from-to)e24-e26
JournalAmerican journal of obstetrics and gynecology
Issue number5
StatePublished - May 1 2009


  • misoprostol
  • prostaglandin F
  • retained placenta
  • second-trimester delivery

ASJC Scopus subject areas

  • Obstetrics and Gynecology


Dive into the research topics of 'Rectal misoprostol vs 15-methyl prostaglandin F<sub>2α</sub> for retained placenta after second-trimester delivery'. Together they form a unique fingerprint.

Cite this