Abstract
In rat hippocampal slices exposed to short duration anoxia, recovery of synaptic transmission was dependent upon the magnitude of the K+o undershoot (K+o drop below resting level) seen following return to normoxic conditions. Because the K+o undershoot is likely to be related to ion pump activity, our results imply that recovery of brain from stroke depends upon how well ion transport and energy production recover.
| Original language | English |
|---|---|
| Pages (from-to) | 178-181 |
| Number of pages | 4 |
| Journal | Brain Research |
| Volume | 402 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 27 1987 |
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Keywords
- Hippocampal slice
- Ion transport
- K undershoot
- Synaptic transmission
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)
Cite this
Recovery of synaptic transmission predicted from extracellular K+ undershoots following brief anoxia in hippocampal slices. / Roberts, Eugene L; Sick, Thomas.
In: Brain Research, Vol. 402, No. 1, 27.01.1987, p. 178-181.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recovery of synaptic transmission predicted from extracellular K+ undershoots following brief anoxia in hippocampal slices
AU - Roberts, Eugene L
AU - Sick, Thomas
PY - 1987/1/27
Y1 - 1987/1/27
N2 - In rat hippocampal slices exposed to short duration anoxia, recovery of synaptic transmission was dependent upon the magnitude of the K+o undershoot (K+o drop below resting level) seen following return to normoxic conditions. Because the K+o undershoot is likely to be related to ion pump activity, our results imply that recovery of brain from stroke depends upon how well ion transport and energy production recover.
AB - In rat hippocampal slices exposed to short duration anoxia, recovery of synaptic transmission was dependent upon the magnitude of the K+o undershoot (K+o drop below resting level) seen following return to normoxic conditions. Because the K+o undershoot is likely to be related to ion pump activity, our results imply that recovery of brain from stroke depends upon how well ion transport and energy production recover.
KW - Hippocampal slice
KW - Ion transport
KW - K undershoot
KW - Synaptic transmission
UR - http://www.scopus.com/inward/record.url?scp=0023156595&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023156595&partnerID=8YFLogxK
U2 - 10.1016/0006-8993(87)91064-X
DO - 10.1016/0006-8993(87)91064-X
M3 - Article
VL - 402
SP - 178
EP - 181
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1
ER -