Recovery of synaptic transmission predicted from extracellular K+ undershoots following brief anoxia in hippocampal slices

Eugene L Roberts, Thomas Sick

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

In rat hippocampal slices exposed to short duration anoxia, recovery of synaptic transmission was dependent upon the magnitude of the K+o undershoot (K+o drop below resting level) seen following return to normoxic conditions. Because the K+o undershoot is likely to be related to ion pump activity, our results imply that recovery of brain from stroke depends upon how well ion transport and energy production recover.

Original languageEnglish
Pages (from-to)178-181
Number of pages4
JournalBrain Research
Volume402
Issue number1
DOIs
StatePublished - Jan 27 1987

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Ion Pumps
Ion Transport
Synaptic Transmission
Stroke
Brain
Hypoxia

Keywords

  • Hippocampal slice
  • Ion transport
  • K undershoot
  • Synaptic transmission

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Recovery of synaptic transmission predicted from extracellular K+ undershoots following brief anoxia in hippocampal slices. / Roberts, Eugene L; Sick, Thomas.

In: Brain Research, Vol. 402, No. 1, 27.01.1987, p. 178-181.

Research output: Contribution to journalArticle

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