Recent developments in the evaluation and treatment of lacrimal gland tumors

David Tse, A. G. Neff, C. B. Onofrey

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Clinical characteristics, diagnostic and pathologic features, biologic behavior, and management protocols for many of the common lacrimal gland disorders are reviewed. Because several of the lacrimal gland fossa lesions are life threatening, thoughtful evaluation based on clinical history, physical examination, and radiographic soft-tissue contour analysis is of paramount importance for proper differentiation. A new treatment approach using intracarotid chemotherapy as an adjuvant therapy to the conventional radical orbitectomy and radiation for adenoid cystic carcinoma is presented. The rationale for intracarotid chemotherapy before exenteration and the treatment protocol are detailed. The sanguine survival outcome of this new treatment modality for a devastating disease, in which successful therapy remains elusive, warrants further studies.

Original languageEnglish
Pages (from-to)663-681
Number of pages19
JournalOphthalmology Clinics of North America
Volume13
Issue number4
StatePublished - Dec 18 2000

Fingerprint

Lacrimal Apparatus
Adenoid Cystic Carcinoma
Neoplasms
Adjuvant Chemotherapy
Clinical Protocols
Physical Examination
Therapeutics
Radiation
Drug Therapy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Recent developments in the evaluation and treatment of lacrimal gland tumors. / Tse, David; Neff, A. G.; Onofrey, C. B.

In: Ophthalmology Clinics of North America, Vol. 13, No. 4, 18.12.2000, p. 663-681.

Research output: Contribution to journalArticle

@article{b5a43c2bb47445f3be5a808e487032e5,
title = "Recent developments in the evaluation and treatment of lacrimal gland tumors",
abstract = "Clinical characteristics, diagnostic and pathologic features, biologic behavior, and management protocols for many of the common lacrimal gland disorders are reviewed. Because several of the lacrimal gland fossa lesions are life threatening, thoughtful evaluation based on clinical history, physical examination, and radiographic soft-tissue contour analysis is of paramount importance for proper differentiation. A new treatment approach using intracarotid chemotherapy as an adjuvant therapy to the conventional radical orbitectomy and radiation for adenoid cystic carcinoma is presented. The rationale for intracarotid chemotherapy before exenteration and the treatment protocol are detailed. The sanguine survival outcome of this new treatment modality for a devastating disease, in which successful therapy remains elusive, warrants further studies.",
author = "David Tse and Neff, {A. G.} and Onofrey, {C. B.}",
year = "2000",
month = "12",
day = "18",
language = "English",
volume = "13",
pages = "663--681",
journal = "Ophthalmology Clinics of North America",
issn = "0896-1549",
publisher = "W.B. Saunders Ltd",
number = "4",

}

TY - JOUR

T1 - Recent developments in the evaluation and treatment of lacrimal gland tumors

AU - Tse, David

AU - Neff, A. G.

AU - Onofrey, C. B.

PY - 2000/12/18

Y1 - 2000/12/18

N2 - Clinical characteristics, diagnostic and pathologic features, biologic behavior, and management protocols for many of the common lacrimal gland disorders are reviewed. Because several of the lacrimal gland fossa lesions are life threatening, thoughtful evaluation based on clinical history, physical examination, and radiographic soft-tissue contour analysis is of paramount importance for proper differentiation. A new treatment approach using intracarotid chemotherapy as an adjuvant therapy to the conventional radical orbitectomy and radiation for adenoid cystic carcinoma is presented. The rationale for intracarotid chemotherapy before exenteration and the treatment protocol are detailed. The sanguine survival outcome of this new treatment modality for a devastating disease, in which successful therapy remains elusive, warrants further studies.

AB - Clinical characteristics, diagnostic and pathologic features, biologic behavior, and management protocols for many of the common lacrimal gland disorders are reviewed. Because several of the lacrimal gland fossa lesions are life threatening, thoughtful evaluation based on clinical history, physical examination, and radiographic soft-tissue contour analysis is of paramount importance for proper differentiation. A new treatment approach using intracarotid chemotherapy as an adjuvant therapy to the conventional radical orbitectomy and radiation for adenoid cystic carcinoma is presented. The rationale for intracarotid chemotherapy before exenteration and the treatment protocol are detailed. The sanguine survival outcome of this new treatment modality for a devastating disease, in which successful therapy remains elusive, warrants further studies.

UR - http://www.scopus.com/inward/record.url?scp=0033673526&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033673526&partnerID=8YFLogxK

M3 - Article

VL - 13

SP - 663

EP - 681

JO - Ophthalmology Clinics of North America

JF - Ophthalmology Clinics of North America

SN - 0896-1549

IS - 4

ER -