Readaptation to the sleep laboratory was assessed in 10 volunteers complaining of insomnia with polysomnographic evidence of disturbed sleep. After an initial 3-night adaptation to the laboratory, subjects slept in the laboratory on 2 consecutive nights per week for 10 weeks and were administered medication according to the following protocol: placebo, Week 1; triazolam (.5 mg), Weeks 2-7; and placebo, Weeks 8-10. Routine sleep recordings were obtained on all laboratory nights. Over the 10 weeks, there were no statistically significant differences (p >.05) between Nights 1 and 2 on the following sleep parameters: percentage wake time, percentage REM, latency to Stage 2, and number of awakenings. It was concluded that readaptation effects in long-term studies are relatively small. The minimal sleep disruption associated with readaptation does not outweigh the advantages of taking repeated laboratory samples of 1 or 2 nights.
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