Abstract
Background: Leishmaniasis is an infection caused by a protozoan parasite belonging to genus Leishmania and transmitted by the Phlebotomus sandfly. Clinical presentations of infection include visceral, cutaneous, and mucocutaneous forms. Leishmaniasis is endemic in Africa, Asia, Europe, South America, and southern part of North America. This infection is extremely rare in the US and is mostly found among travelers coming from endemic areas. Cases of cutaneous and visceral leishmaniasis have been reported in organ transplant recipients in endemic areas. Case report: We describe a case of cutaneous leishmaniasis in a kidney transplant patient, originally from Bolivia, who resides in the area known to be non-endemic for leishmaniasis and who is known not to travel within or outside of the US after the transplantation. Results: Histologic examination of cutaneous lesion revealed extensive subcutaneous lymphohistiocytic inflammation with clusters of amastigote within histiocytes. Conclusion: To our knowledge, this is the first case of cutaneous leishmaniasis in a kidney transplant patient residing in the US in an area known to be non-endemic for leishmaniasis, probably after reactivation of a previously dormant infection acquired outside of the US at least 9 months prior to developing clinical symptoms.
| Original language | English |
|---|---|
| Pages (from-to) | 701-704 |
| Number of pages | 4 |
| Journal | Journal of Cutaneous Pathology |
| Volume | 33 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1 2006 |
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ASJC Scopus subject areas
- Dermatology
- Pathology and Forensic Medicine
Cite this
Reactivation of dormant cutaneous Leishmania infection in a kidney transplant patient. / Mirzabeigi, Marjan; Farooq, Uzma; Baraniak, Sean; Dowdy, Lorraine; Ciancio, Gaetano; Vincek, Vladimir.
In: Journal of Cutaneous Pathology, Vol. 33, No. 10, 01.10.2006, p. 701-704.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Reactivation of dormant cutaneous Leishmania infection in a kidney transplant patient
AU - Mirzabeigi, Marjan
AU - Farooq, Uzma
AU - Baraniak, Sean
AU - Dowdy, Lorraine
AU - Ciancio, Gaetano
AU - Vincek, Vladimir
PY - 2006/10/1
Y1 - 2006/10/1
N2 - Background: Leishmaniasis is an infection caused by a protozoan parasite belonging to genus Leishmania and transmitted by the Phlebotomus sandfly. Clinical presentations of infection include visceral, cutaneous, and mucocutaneous forms. Leishmaniasis is endemic in Africa, Asia, Europe, South America, and southern part of North America. This infection is extremely rare in the US and is mostly found among travelers coming from endemic areas. Cases of cutaneous and visceral leishmaniasis have been reported in organ transplant recipients in endemic areas. Case report: We describe a case of cutaneous leishmaniasis in a kidney transplant patient, originally from Bolivia, who resides in the area known to be non-endemic for leishmaniasis and who is known not to travel within or outside of the US after the transplantation. Results: Histologic examination of cutaneous lesion revealed extensive subcutaneous lymphohistiocytic inflammation with clusters of amastigote within histiocytes. Conclusion: To our knowledge, this is the first case of cutaneous leishmaniasis in a kidney transplant patient residing in the US in an area known to be non-endemic for leishmaniasis, probably after reactivation of a previously dormant infection acquired outside of the US at least 9 months prior to developing clinical symptoms.
AB - Background: Leishmaniasis is an infection caused by a protozoan parasite belonging to genus Leishmania and transmitted by the Phlebotomus sandfly. Clinical presentations of infection include visceral, cutaneous, and mucocutaneous forms. Leishmaniasis is endemic in Africa, Asia, Europe, South America, and southern part of North America. This infection is extremely rare in the US and is mostly found among travelers coming from endemic areas. Cases of cutaneous and visceral leishmaniasis have been reported in organ transplant recipients in endemic areas. Case report: We describe a case of cutaneous leishmaniasis in a kidney transplant patient, originally from Bolivia, who resides in the area known to be non-endemic for leishmaniasis and who is known not to travel within or outside of the US after the transplantation. Results: Histologic examination of cutaneous lesion revealed extensive subcutaneous lymphohistiocytic inflammation with clusters of amastigote within histiocytes. Conclusion: To our knowledge, this is the first case of cutaneous leishmaniasis in a kidney transplant patient residing in the US in an area known to be non-endemic for leishmaniasis, probably after reactivation of a previously dormant infection acquired outside of the US at least 9 months prior to developing clinical symptoms.
UR - http://www.scopus.com/inward/record.url?scp=33749552873&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749552873&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0560.2006.00532.x
DO - 10.1111/j.1600-0560.2006.00532.x
M3 - Article
C2 - 17026523
AN - SCOPUS:33749552873
VL - 33
SP - 701
EP - 704
JO - Journal of Cutaneous Pathology
JF - Journal of Cutaneous Pathology
SN - 0303-6987
IS - 10
ER -