| Original language | English (US) |
|---|---|
| Pages (from-to) | S11-S16 |
| Journal | The Journal of Pediatrics |
| Volume | 116 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1990 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
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Rationale of the growth failure in children with renal diseases study. / Chan, James C.M.; Greifer, Ira; Boineau, Frank G.; Mendoza, Stanley A.; McEnery, Paul T.; Strife, C. Frederic; Abitbol, Carolyn L.; Stapleton, F. Bruder; Roy, Shane; Strauss, Jose.
In: The Journal of Pediatrics, Vol. 116, No. 2, 02.1990, p. S11-S16.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Rationale of the growth failure in children with renal diseases study
AU - Chan, James C.M.
AU - Greifer, Ira
AU - Boineau, Frank G.
AU - Mendoza, Stanley A.
AU - McEnery, Paul T.
AU - Strife, C. Frederic
AU - Abitbol, Carolyn L.
AU - Stapleton, F. Bruder
AU - Roy, Shane
AU - Strauss, Jose
N1 - Funding Information: Chesney et al. 1 and Chan and DeLuca 2 reported, respectively, on the utility of 1,25-dihydroxyvitamin D3 and its analog, la-hydroxyvitamin D3, in reversing growth failure resulting from renal osteodystrophy in children with end-stage renal disease. Linear growth is accelerated in at least 73% of such children receiving 1,25-dihydroxyvitamin D3, and bone age comparisons demonstrate growth averaging 1.5-fold over that expected for age. Furthermore, only 33% of children older than 12 years of age can be expected to attain such accelerated linear growth. 3 Finally, as shown in the Figure, children who are undergoing hemodialysis, especially those whose age is greater than 12 years, donot respond as well to such treatment. This finding agrees with earlier observations that children with chronic renal failure, Supported by National Institutes of Health grants R01 DK 31370 and R01 DK 32431. Reprint requests: James C. M. Chan, MD, Medical College of Virginia, Box 498 MCV Station, Richmond, VA 23298-0498.
PY - 1990/2
Y1 - 1990/2
UR - http://www.scopus.com/inward/record.url?scp=0025174018&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025174018&partnerID=8YFLogxK
U2 - 10.1016/S0022-3476(05)82917-8
DO - 10.1016/S0022-3476(05)82917-8
M3 - Article
C2 - 2405129
AN - SCOPUS:0025174018
VL - 116
SP - S11-S16
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 2
ER -