Rates of Reoperation and Abnormal Binocularity Following Strabismus Surgery in Children

Christopher T. Leffler, Kamyar Vaziri, Stephen Schwartz, Kara M Cavuoto, Craig McKeown, Krishna Kishor, Adam C. Janot

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12 Citations (Scopus)

Abstract

Purpose: To determine predictors of reoperation and abnormal binocularity outcomes (including amblyopia and diplopia) following pediatric strabismus surgery. Design: Retrospective cross-sectional study. Methods: setting: Review of a national insurance database. study population: Children under age 18 years having strabismus procedures between 2007 and 2013. interventions: Adjustable- or fixed-suture strabismus surgery, or botulinum toxin injection. outcome measures: Reoperation or diagnosis of abnormal binocularity in the first postoperative year. Results: Of 11 115 children having strabismus procedures, 851 (7.7%) underwent reoperation. The reoperation rate was 7.4% for fixed-suture surgeries, 9.6% for adjustable-suture surgeries (P = .18), and 44.9% for botulinum injections (P <.001). Age under 2 years was associated with higher reoperation and abnormal binocularity rates (P <.001). For horizontal strabismus, the postoperative abnormal binocularity rate was 12.8% for fixed-suture surgery and 26.5% for botulinum injection (P = .005). Reoperation rates tended to be higher with adjustable sutures (odds ratio [OR] 1.69, 95% confidence interval [CI] 0.94-3.03, P = .08) or botulinum toxin injection (OR 10.36, 95% CI 5.75-18.66, P <.001) and lower with 3- or 4-muscle surgery (P = .001). Esotropia, hyperopia, and botulinum injection were independently associated with higher rates of postoperative abnormal binocularity (P ≤ .005). For vertical surgeries, predictors of reoperation were adjustable-suture use (OR 2.51, P = .10) and superior oblique surgery (OR 2.36, P <.001). Conclusions: Adjustable sutures were not associated with a lower reoperation rate in children. Younger age, esotropia, hyperopia, and botulinum injection were associated with postoperative abnormal binocularity. Superior oblique surgery and botulinum injection were associated with higher rates of reoperation.

Original languageEnglish (US)
JournalAmerican Journal of Ophthalmology
DOIs
StateAccepted/In press - 2015

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Strabismus
Reoperation
Sutures
Injections
Odds Ratio
Hyperopia
Esotropia
Botulinum Toxins
Confidence Intervals
Amblyopia
Diplopia
Insurance
Cross-Sectional Studies
Outcome Assessment (Health Care)
Databases
Pediatrics
Muscles

ASJC Scopus subject areas

  • Ophthalmology

Cite this

@article{67c7c729071148d0bccddfcc6f14fe86,
title = "Rates of Reoperation and Abnormal Binocularity Following Strabismus Surgery in Children",
abstract = "Purpose: To determine predictors of reoperation and abnormal binocularity outcomes (including amblyopia and diplopia) following pediatric strabismus surgery. Design: Retrospective cross-sectional study. Methods: setting: Review of a national insurance database. study population: Children under age 18 years having strabismus procedures between 2007 and 2013. interventions: Adjustable- or fixed-suture strabismus surgery, or botulinum toxin injection. outcome measures: Reoperation or diagnosis of abnormal binocularity in the first postoperative year. Results: Of 11 115 children having strabismus procedures, 851 (7.7{\%}) underwent reoperation. The reoperation rate was 7.4{\%} for fixed-suture surgeries, 9.6{\%} for adjustable-suture surgeries (P = .18), and 44.9{\%} for botulinum injections (P <.001). Age under 2 years was associated with higher reoperation and abnormal binocularity rates (P <.001). For horizontal strabismus, the postoperative abnormal binocularity rate was 12.8{\%} for fixed-suture surgery and 26.5{\%} for botulinum injection (P = .005). Reoperation rates tended to be higher with adjustable sutures (odds ratio [OR] 1.69, 95{\%} confidence interval [CI] 0.94-3.03, P = .08) or botulinum toxin injection (OR 10.36, 95{\%} CI 5.75-18.66, P <.001) and lower with 3- or 4-muscle surgery (P = .001). Esotropia, hyperopia, and botulinum injection were independently associated with higher rates of postoperative abnormal binocularity (P ≤ .005). For vertical surgeries, predictors of reoperation were adjustable-suture use (OR 2.51, P = .10) and superior oblique surgery (OR 2.36, P <.001). Conclusions: Adjustable sutures were not associated with a lower reoperation rate in children. Younger age, esotropia, hyperopia, and botulinum injection were associated with postoperative abnormal binocularity. Superior oblique surgery and botulinum injection were associated with higher rates of reoperation.",
author = "Leffler, {Christopher T.} and Kamyar Vaziri and Stephen Schwartz and Cavuoto, {Kara M} and Craig McKeown and Krishna Kishor and Janot, {Adam C.}",
year = "2015",
doi = "10.1016/j.ajo.2015.10.022",
language = "English (US)",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
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T1 - Rates of Reoperation and Abnormal Binocularity Following Strabismus Surgery in Children

AU - Leffler, Christopher T.

AU - Vaziri, Kamyar

AU - Schwartz, Stephen

AU - Cavuoto, Kara M

AU - McKeown, Craig

AU - Kishor, Krishna

AU - Janot, Adam C.

PY - 2015

Y1 - 2015

N2 - Purpose: To determine predictors of reoperation and abnormal binocularity outcomes (including amblyopia and diplopia) following pediatric strabismus surgery. Design: Retrospective cross-sectional study. Methods: setting: Review of a national insurance database. study population: Children under age 18 years having strabismus procedures between 2007 and 2013. interventions: Adjustable- or fixed-suture strabismus surgery, or botulinum toxin injection. outcome measures: Reoperation or diagnosis of abnormal binocularity in the first postoperative year. Results: Of 11 115 children having strabismus procedures, 851 (7.7%) underwent reoperation. The reoperation rate was 7.4% for fixed-suture surgeries, 9.6% for adjustable-suture surgeries (P = .18), and 44.9% for botulinum injections (P <.001). Age under 2 years was associated with higher reoperation and abnormal binocularity rates (P <.001). For horizontal strabismus, the postoperative abnormal binocularity rate was 12.8% for fixed-suture surgery and 26.5% for botulinum injection (P = .005). Reoperation rates tended to be higher with adjustable sutures (odds ratio [OR] 1.69, 95% confidence interval [CI] 0.94-3.03, P = .08) or botulinum toxin injection (OR 10.36, 95% CI 5.75-18.66, P <.001) and lower with 3- or 4-muscle surgery (P = .001). Esotropia, hyperopia, and botulinum injection were independently associated with higher rates of postoperative abnormal binocularity (P ≤ .005). For vertical surgeries, predictors of reoperation were adjustable-suture use (OR 2.51, P = .10) and superior oblique surgery (OR 2.36, P <.001). Conclusions: Adjustable sutures were not associated with a lower reoperation rate in children. Younger age, esotropia, hyperopia, and botulinum injection were associated with postoperative abnormal binocularity. Superior oblique surgery and botulinum injection were associated with higher rates of reoperation.

AB - Purpose: To determine predictors of reoperation and abnormal binocularity outcomes (including amblyopia and diplopia) following pediatric strabismus surgery. Design: Retrospective cross-sectional study. Methods: setting: Review of a national insurance database. study population: Children under age 18 years having strabismus procedures between 2007 and 2013. interventions: Adjustable- or fixed-suture strabismus surgery, or botulinum toxin injection. outcome measures: Reoperation or diagnosis of abnormal binocularity in the first postoperative year. Results: Of 11 115 children having strabismus procedures, 851 (7.7%) underwent reoperation. The reoperation rate was 7.4% for fixed-suture surgeries, 9.6% for adjustable-suture surgeries (P = .18), and 44.9% for botulinum injections (P <.001). Age under 2 years was associated with higher reoperation and abnormal binocularity rates (P <.001). For horizontal strabismus, the postoperative abnormal binocularity rate was 12.8% for fixed-suture surgery and 26.5% for botulinum injection (P = .005). Reoperation rates tended to be higher with adjustable sutures (odds ratio [OR] 1.69, 95% confidence interval [CI] 0.94-3.03, P = .08) or botulinum toxin injection (OR 10.36, 95% CI 5.75-18.66, P <.001) and lower with 3- or 4-muscle surgery (P = .001). Esotropia, hyperopia, and botulinum injection were independently associated with higher rates of postoperative abnormal binocularity (P ≤ .005). For vertical surgeries, predictors of reoperation were adjustable-suture use (OR 2.51, P = .10) and superior oblique surgery (OR 2.36, P <.001). Conclusions: Adjustable sutures were not associated with a lower reoperation rate in children. Younger age, esotropia, hyperopia, and botulinum injection were associated with postoperative abnormal binocularity. Superior oblique surgery and botulinum injection were associated with higher rates of reoperation.

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