Rates and Correlates of Syphilis Reinfection in Men Who Have Sex with Men

Jennifer Jain, Glenn Milo Santos, Susan Scheer, Steve Gibson, Pierre Cédric Crouch, Robert Kohn, Walter Chang, Adam Carrico

Research output: Contribution to journalArticle

4 Scopus citations


Purpose: This study examined rates and correlates of syphilis reinfection in men who have sex with men (MSM). Methods: From 2012 to 2015, time to reinfection was assessed in 323 MSM receiving initial treatment for syphilis in San Francisco. Results: One in five men was reinfected (71/323; 22%). The rate of syphilis reinfection was greater among HIVinfected men (adjusted hazard ratio [aHR] = 1.96; 95% confidence interval [95% CI] = 1.16?3.31) and ketamine users (aHR = 2.76; 95% CI = 1.09?7.00). Conclusion: Expanded prevention efforts are needed with HIV-infected and substance-using MSM to reduce the burden of reinfection in this population.

Original languageEnglish (US)
Pages (from-to)232-236
Number of pages5
JournalLGBT Health
Issue number3
StatePublished - Jun 1 2017



  • HIV
  • men who have sex with men (MSM)
  • repeat syphilis
  • substance use

ASJC Scopus subject areas

  • Dermatology
  • Obstetrics and Gynecology
  • Public Health, Environmental and Occupational Health
  • Psychiatry and Mental health
  • Urology

Cite this

Jain, J., Santos, G. M., Scheer, S., Gibson, S., Crouch, P. C., Kohn, R., Chang, W., & Carrico, A. (2017). Rates and Correlates of Syphilis Reinfection in Men Who Have Sex with Men. LGBT Health, 4(3), 232-236. https://doi.org/10.1089/lgbt.2016.0095