Rapidly progressive non-A, non-B hepatitis in patients with human immunodeficiency virus infection

Paul Martin, Adrian M. Di Bisceglie, Chris Kassianides, Mauricio Lisker-Melman, Jay H. Hoofnagle

Research output: Contribution to journalArticle

209 Scopus citations


No information is available on the role of non-A, non-B hepatitis in the various hepatic abnormalities described in patients with the acquired immune deficiency syndrome. Of 97 patients referred with suspected non-A, non-B hepatitis, 3 were found to have antibody to the human immunodeficiency virus. These latter 3 patients all developed symptomatic cirrhosis within 3 yr of onset of hepatitis. Such a rapid progression of liver disease was rare in patients with non-A, non-B hepatitis who did not have simultaneous human immunodeficiency infection. These findings suggest that human immunodeficiency virus infection may potentiate the liver injury of chronic non-A, non-B hepatitis.

Original languageEnglish (US)
Pages (from-to)1559-1561
Number of pages3
Issue number6
StatePublished - Dec 1989
Externally publishedYes


ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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