Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology

Anat Galor, Gerri S. Hall, Gary W. Procop, Marion Tuohy, Michael E. Millstein, Bennie H. Jeng

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Purpose: To describe a new technique, pyrosequencing, which allows for the rapid identification of Mycobacterium and Nocardia species. Design: Interventional case report. Methods: The medical records of a patient presenting with an infectious keratitis were reviewed. Results: A case of Nocardia abscessus/arthrititis/asiatica keratitis was diagnosed in a young individual with the aid of pyrosequencing technology. Based on presumed antibiotic sensitivities, therapy with topical trimethoprim-sulfamethoxazole eyedrops was initiated, and the infection was cleared rapidly with minimal residual scarring. Conclusions: Pyrosequencing may be a useful tool in aiding the rapid diagnosis and treatment of ocular infections caused by slow-growing pathogens.

Original languageEnglish
Pages (from-to)182-183
Number of pages2
JournalAmerican Journal of Ophthalmology
Volume143
Issue number1
DOIs
StatePublished - Jan 1 2007
Externally publishedYes

Fingerprint

Nocardia
Keratitis
Technology
Eye Infections
Ophthalmic Solutions
Sulfamethoxazole Drug Combination Trimethoprim
Mycobacterium
Cicatrix
Medical Records
Anti-Bacterial Agents
Therapeutics
Infection

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology. / Galor, Anat; Hall, Gerri S.; Procop, Gary W.; Tuohy, Marion; Millstein, Michael E.; Jeng, Bennie H.

In: American Journal of Ophthalmology, Vol. 143, No. 1, 01.01.2007, p. 182-183.

Research output: Contribution to journalArticle

Galor, Anat ; Hall, Gerri S. ; Procop, Gary W. ; Tuohy, Marion ; Millstein, Michael E. ; Jeng, Bennie H. / Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology. In: American Journal of Ophthalmology. 2007 ; Vol. 143, No. 1. pp. 182-183.
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