Abstract
Purpose: To describe a new technique, pyrosequencing, which allows for the rapid identification of Mycobacterium and Nocardia species. Design: Interventional case report. Methods: The medical records of a patient presenting with an infectious keratitis were reviewed. Results: A case of Nocardia abscessus/arthrititis/asiatica keratitis was diagnosed in a young individual with the aid of pyrosequencing technology. Based on presumed antibiotic sensitivities, therapy with topical trimethoprim-sulfamethoxazole eyedrops was initiated, and the infection was cleared rapidly with minimal residual scarring. Conclusions: Pyrosequencing may be a useful tool in aiding the rapid diagnosis and treatment of ocular infections caused by slow-growing pathogens.
| Original language | English |
|---|---|
| Pages (from-to) | 182-183 |
| Number of pages | 2 |
| Journal | American Journal of Ophthalmology |
| Volume | 143 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2007 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology. / Galor, Anat; Hall, Gerri S.; Procop, Gary W.; Tuohy, Marion; Millstein, Michael E.; Jeng, Bennie H.
In: American Journal of Ophthalmology, Vol. 143, No. 1, 01.01.2007, p. 182-183.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology
AU - Galor, Anat
AU - Hall, Gerri S.
AU - Procop, Gary W.
AU - Tuohy, Marion
AU - Millstein, Michael E.
AU - Jeng, Bennie H.
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Purpose: To describe a new technique, pyrosequencing, which allows for the rapid identification of Mycobacterium and Nocardia species. Design: Interventional case report. Methods: The medical records of a patient presenting with an infectious keratitis were reviewed. Results: A case of Nocardia abscessus/arthrititis/asiatica keratitis was diagnosed in a young individual with the aid of pyrosequencing technology. Based on presumed antibiotic sensitivities, therapy with topical trimethoprim-sulfamethoxazole eyedrops was initiated, and the infection was cleared rapidly with minimal residual scarring. Conclusions: Pyrosequencing may be a useful tool in aiding the rapid diagnosis and treatment of ocular infections caused by slow-growing pathogens.
AB - Purpose: To describe a new technique, pyrosequencing, which allows for the rapid identification of Mycobacterium and Nocardia species. Design: Interventional case report. Methods: The medical records of a patient presenting with an infectious keratitis were reviewed. Results: A case of Nocardia abscessus/arthrititis/asiatica keratitis was diagnosed in a young individual with the aid of pyrosequencing technology. Based on presumed antibiotic sensitivities, therapy with topical trimethoprim-sulfamethoxazole eyedrops was initiated, and the infection was cleared rapidly with minimal residual scarring. Conclusions: Pyrosequencing may be a useful tool in aiding the rapid diagnosis and treatment of ocular infections caused by slow-growing pathogens.
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UR - http://www.scopus.com/inward/citedby.url?scp=33845498650&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2006.07.036
DO - 10.1016/j.ajo.2006.07.036
M3 - Article
C2 - 17188068
AN - SCOPUS:33845498650
VL - 143
SP - 182
EP - 183
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 1
ER -