Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology

Anat Galor; Gerri S. Hall; Gary W. Procop; Marion Tuohy; Michael E. Millstein; Bennie H. Jeng

doi:10.1016/j.ajo.2006.07.036

Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology

Anat Galor, Gerri S. Hall, Gary W. Procop, Marion Tuohy, Michael E. Millstein, Bennie H. Jeng

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Purpose: To describe a new technique, pyrosequencing, which allows for the rapid identification of Mycobacterium and Nocardia species. Design: Interventional case report. Methods: The medical records of a patient presenting with an infectious keratitis were reviewed. Results: A case of Nocardia abscessus/arthrititis/asiatica keratitis was diagnosed in a young individual with the aid of pyrosequencing technology. Based on presumed antibiotic sensitivities, therapy with topical trimethoprim-sulfamethoxazole eyedrops was initiated, and the infection was cleared rapidly with minimal residual scarring. Conclusions: Pyrosequencing may be a useful tool in aiding the rapid diagnosis and treatment of ocular infections caused by slow-growing pathogens.

Original language	English (US)
Pages (from-to)	182-183
Number of pages	2
Journal	American journal of ophthalmology
Volume	143
Issue number	1
DOIs	https://doi.org/10.1016/j.ajo.2006.07.036
State	Published - Jan 2007
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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abstract = "Purpose: To describe a new technique, pyrosequencing, which allows for the rapid identification of Mycobacterium and Nocardia species. Design: Interventional case report. Methods: The medical records of a patient presenting with an infectious keratitis were reviewed. Results: A case of Nocardia abscessus/arthrititis/asiatica keratitis was diagnosed in a young individual with the aid of pyrosequencing technology. Based on presumed antibiotic sensitivities, therapy with topical trimethoprim-sulfamethoxazole eyedrops was initiated, and the infection was cleared rapidly with minimal residual scarring. Conclusions: Pyrosequencing may be a useful tool in aiding the rapid diagnosis and treatment of ocular infections caused by slow-growing pathogens.",

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AU - Galor, Anat

AU - Hall, Gerri S.

AU - Procop, Gary W.

AU - Tuohy, Marion

AU - Millstein, Michael E.

AU - Jeng, Bennie H.

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Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology

Abstract

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