TY - JOUR
T1 - Rapid Species Determination of Nocardia Keratitis Using Pyrosequencing Technology
AU - Galor, Anat
AU - Hall, Gerri S.
AU - Procop, Gary W.
AU - Tuohy, Marion
AU - Millstein, Michael E.
AU - Jeng, Bennie H.
PY - 2007/1
Y1 - 2007/1
N2 - Purpose: To describe a new technique, pyrosequencing, which allows for the rapid identification of Mycobacterium and Nocardia species. Design: Interventional case report. Methods: The medical records of a patient presenting with an infectious keratitis were reviewed. Results: A case of Nocardia abscessus/arthrititis/asiatica keratitis was diagnosed in a young individual with the aid of pyrosequencing technology. Based on presumed antibiotic sensitivities, therapy with topical trimethoprim-sulfamethoxazole eyedrops was initiated, and the infection was cleared rapidly with minimal residual scarring. Conclusions: Pyrosequencing may be a useful tool in aiding the rapid diagnosis and treatment of ocular infections caused by slow-growing pathogens.
AB - Purpose: To describe a new technique, pyrosequencing, which allows for the rapid identification of Mycobacterium and Nocardia species. Design: Interventional case report. Methods: The medical records of a patient presenting with an infectious keratitis were reviewed. Results: A case of Nocardia abscessus/arthrititis/asiatica keratitis was diagnosed in a young individual with the aid of pyrosequencing technology. Based on presumed antibiotic sensitivities, therapy with topical trimethoprim-sulfamethoxazole eyedrops was initiated, and the infection was cleared rapidly with minimal residual scarring. Conclusions: Pyrosequencing may be a useful tool in aiding the rapid diagnosis and treatment of ocular infections caused by slow-growing pathogens.
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U2 - 10.1016/j.ajo.2006.07.036
DO - 10.1016/j.ajo.2006.07.036
M3 - Article
C2 - 17188068
AN - SCOPUS:33845498650
VL - 143
SP - 182
EP - 183
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 1
ER -