Rapid involution of large cardiac rhabdomyomas with everolimus therapy.

Ashish Garg, Sudheer Gorla, Richard Kardon, Sethuraman Swaminathan

Research output: Contribution to journalArticlepeer-review


Rhabdomyoma of the fetal heart is a rare disease accounting for about 1% of all fetal cardiac structural anomalies. They are often found in association with tuberous sclerosis complex. Large cardiac rhabdomyomas can compromise the cardiac function. We report a case of multiple large rhabdomyomas of the right and left ventricles, affecting the cardiac function, which was successfully treated with the chemotherapeutic and immunosuppressive medication everolimus, in a neonate with genetically confirmed tuberous sclerosis complex with multisystem manifestations. There was rapid involution of the tumors in response to everolimus therapy in this infant.
Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalWorld Journal for Pediatric and Congenital Hearth Surgery
StatePublished - May 10 2019


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