Rapid involution of large cardiac rhabdomyomas with everolimus therapy.

Ashish Garg, Sudheer Gorla, Richard Kardon, Sethuraman Swaminathan

Research output: Contribution to journal › Article

Abstract

Rhabdomyoma of the fetal heart is a rare disease accounting for about 1% of all fetal cardiac structural anomalies. They are often found in association with tuberous sclerosis complex. Large cardiac rhabdomyomas can compromise the cardiac function. We report a case of multiple large rhabdomyomas of the right and left ventricles, affecting the cardiac function, which was successfully treated with the chemotherapeutic and immunosuppressive medication everolimus, in a neonate with genetically confirmed tuberous sclerosis complex with multisystem manifestations. There was rapid involution of the tumors in response to everolimus therapy in this infant.
Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalWorld Journal for Pediatric and Congenital Hearth Surgery
DOIs
StatePublished - May 10 2019

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Rhabdomyoma
Tuberous Sclerosis
Heart Ventricles
Fetal Heart
Immunosuppressive Agents
Rare Diseases
Therapeutics
Newborn Infant
Everolimus
Neoplasms

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Rapid involution of large cardiac rhabdomyomas with everolimus therapy. / Garg, Ashish; Gorla, Sudheer; Kardon, Richard; Swaminathan, Sethuraman.

In: World Journal for Pediatric and Congenital Hearth Surgery, 10.05.2019, p. 1-3.

Research output: Contribution to journal › Article

Garg, A, Gorla, S, Kardon, R & Swaminathan, S 2019, 'Rapid involution of large cardiac rhabdomyomas with everolimus therapy.', World Journal for Pediatric and Congenital Hearth Surgery, pp. 1-3. https://doi.org/10.1177/2150135118822711
Garg A, Gorla S, Kardon R, Swaminathan S. Rapid involution of large cardiac rhabdomyomas with everolimus therapy. World Journal for Pediatric and Congenital Hearth Surgery. 2019 May 10;1-3. https://doi.org/10.1177/2150135118822711
Garg, Ashish ; Gorla, Sudheer ; Kardon, Richard ; Swaminathan, Sethuraman. / Rapid involution of large cardiac rhabdomyomas with everolimus therapy. In: World Journal for Pediatric and Congenital Hearth Surgery. 2019 ; pp. 1-3.
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