Rapid Identification and Investigation of an HIV Risk Network Among People Who Inject Drugs –Miami, FL, 2018

Hansel Tookes, Tyler S. Bartholomew, Shana Geary, James Matthias, Karalee Poschman, Carina Blackmore, Celeste Philip, Edward Suarez, David W. Forrest, Allan E. Rodriguez, Michael A. Kolber, Felicia Knaul, Leah Colucci, Emma Spencer

Research output: Contribution to journalArticle

Abstract

Prevention of HIV outbreaks among people who inject drugs remains a challenge to ending the HIV epidemic in the United States. The first legal syringe services program (SSP) in Florida implemented routine screening in 2018 leading to the identification of ten anonymous HIV seroconversions. The SSP collaborated with the Department of Health to conduct an epidemiologic investigation. All seven acute HIV seroconversions were linked to care (86% within 30 days) and achieved viral suppression (mean 70 days). Six of the seven individuals are epidemiologically and/or socially linked to at least two other seroconversions. Analysis of the HIV genotypes revealed that two individuals are connected molecularly at 0.5% genetic distance. We identified a risk network with complex transmission dynamics that could not be explained by epidemiological methods or molecular analyses alone. Providing wrap-around services through the SSP, including routine screening, intensive linkage and patient navigation, could be an effective model for achieving viral suppression for people who inject drugs.

Original languageEnglish (US)
JournalAIDS and Behavior
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Syringes
HIV Seropositivity
HIV
Patient Navigation
Pharmaceutical Preparations
Epidemiologic Methods
Disease Outbreaks
Genotype
Health

Keywords

  • HIV
  • Molecular surveillance
  • Outbreak investigation
  • People who inject drugs

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Tookes, H., Bartholomew, T. S., Geary, S., Matthias, J., Poschman, K., Blackmore, C., ... Spencer, E. (Accepted/In press). Rapid Identification and Investigation of an HIV Risk Network Among People Who Inject Drugs –Miami, FL, 2018. AIDS and Behavior. https://doi.org/10.1007/s10461-019-02680-9

Rapid Identification and Investigation of an HIV Risk Network Among People Who Inject Drugs –Miami, FL, 2018. / Tookes, Hansel; Bartholomew, Tyler S.; Geary, Shana; Matthias, James; Poschman, Karalee; Blackmore, Carina; Philip, Celeste; Suarez, Edward; Forrest, David W.; Rodriguez, Allan E.; Kolber, Michael A.; Knaul, Felicia; Colucci, Leah; Spencer, Emma.

In: AIDS and Behavior, 01.01.2019.

Research output: Contribution to journalArticle

Tookes, Hansel ; Bartholomew, Tyler S. ; Geary, Shana ; Matthias, James ; Poschman, Karalee ; Blackmore, Carina ; Philip, Celeste ; Suarez, Edward ; Forrest, David W. ; Rodriguez, Allan E. ; Kolber, Michael A. ; Knaul, Felicia ; Colucci, Leah ; Spencer, Emma. / Rapid Identification and Investigation of an HIV Risk Network Among People Who Inject Drugs –Miami, FL, 2018. In: AIDS and Behavior. 2019.
@article{a479f21c3ace47dbb8771dedb5f8a3bf,
title = "Rapid Identification and Investigation of an HIV Risk Network Among People Who Inject Drugs –Miami, FL, 2018",
abstract = "Prevention of HIV outbreaks among people who inject drugs remains a challenge to ending the HIV epidemic in the United States. The first legal syringe services program (SSP) in Florida implemented routine screening in 2018 leading to the identification of ten anonymous HIV seroconversions. The SSP collaborated with the Department of Health to conduct an epidemiologic investigation. All seven acute HIV seroconversions were linked to care (86{\%} within 30 days) and achieved viral suppression (mean 70 days). Six of the seven individuals are epidemiologically and/or socially linked to at least two other seroconversions. Analysis of the HIV genotypes revealed that two individuals are connected molecularly at 0.5{\%} genetic distance. We identified a risk network with complex transmission dynamics that could not be explained by epidemiological methods or molecular analyses alone. Providing wrap-around services through the SSP, including routine screening, intensive linkage and patient navigation, could be an effective model for achieving viral suppression for people who inject drugs.",
keywords = "HIV, Molecular surveillance, Outbreak investigation, People who inject drugs",
author = "Hansel Tookes and Bartholomew, {Tyler S.} and Shana Geary and James Matthias and Karalee Poschman and Carina Blackmore and Celeste Philip and Edward Suarez and Forrest, {David W.} and Rodriguez, {Allan E.} and Kolber, {Michael A.} and Felicia Knaul and Leah Colucci and Emma Spencer",
year = "2019",
month = "1",
day = "1",
doi = "10.1007/s10461-019-02680-9",
language = "English (US)",
journal = "AIDS and Behavior",
issn = "1090-7165",
publisher = "Springer New York",

}

TY - JOUR

T1 - Rapid Identification and Investigation of an HIV Risk Network Among People Who Inject Drugs –Miami, FL, 2018

AU - Tookes, Hansel

AU - Bartholomew, Tyler S.

AU - Geary, Shana

AU - Matthias, James

AU - Poschman, Karalee

AU - Blackmore, Carina

AU - Philip, Celeste

AU - Suarez, Edward

AU - Forrest, David W.

AU - Rodriguez, Allan E.

AU - Kolber, Michael A.

AU - Knaul, Felicia

AU - Colucci, Leah

AU - Spencer, Emma

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Prevention of HIV outbreaks among people who inject drugs remains a challenge to ending the HIV epidemic in the United States. The first legal syringe services program (SSP) in Florida implemented routine screening in 2018 leading to the identification of ten anonymous HIV seroconversions. The SSP collaborated with the Department of Health to conduct an epidemiologic investigation. All seven acute HIV seroconversions were linked to care (86% within 30 days) and achieved viral suppression (mean 70 days). Six of the seven individuals are epidemiologically and/or socially linked to at least two other seroconversions. Analysis of the HIV genotypes revealed that two individuals are connected molecularly at 0.5% genetic distance. We identified a risk network with complex transmission dynamics that could not be explained by epidemiological methods or molecular analyses alone. Providing wrap-around services through the SSP, including routine screening, intensive linkage and patient navigation, could be an effective model for achieving viral suppression for people who inject drugs.

AB - Prevention of HIV outbreaks among people who inject drugs remains a challenge to ending the HIV epidemic in the United States. The first legal syringe services program (SSP) in Florida implemented routine screening in 2018 leading to the identification of ten anonymous HIV seroconversions. The SSP collaborated with the Department of Health to conduct an epidemiologic investigation. All seven acute HIV seroconversions were linked to care (86% within 30 days) and achieved viral suppression (mean 70 days). Six of the seven individuals are epidemiologically and/or socially linked to at least two other seroconversions. Analysis of the HIV genotypes revealed that two individuals are connected molecularly at 0.5% genetic distance. We identified a risk network with complex transmission dynamics that could not be explained by epidemiological methods or molecular analyses alone. Providing wrap-around services through the SSP, including routine screening, intensive linkage and patient navigation, could be an effective model for achieving viral suppression for people who inject drugs.

KW - HIV

KW - Molecular surveillance

KW - Outbreak investigation

KW - People who inject drugs

UR - http://www.scopus.com/inward/record.url?scp=85074021859&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85074021859&partnerID=8YFLogxK

U2 - 10.1007/s10461-019-02680-9

DO - 10.1007/s10461-019-02680-9

M3 - Article

AN - SCOPUS:85074021859

JO - AIDS and Behavior

JF - AIDS and Behavior

SN - 1090-7165

ER -