Rapid healing of scar-associated chronic wounds after ablative fractional resurfacing

Peter R. Shumaker, Julia M. Kwan, Evangelos V Badiavas, Jill Waibel, Stephen C Davis, Nathan S. Uebelhoer

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Background: Skin compromised by traumatic scars and contractures can manifest decreased resistance to shearing and other forces, while increased tension and skin fragility contribute to chronic erosions and ulcerations. Chronic wounds possess inflammatory mediator profiles and other characteristics, such as the presence of biofilms, that can inhibit healing. Observations: Three patients with multiple traumatic scars related to blast injuries initiated a course of ablative fractional laser therapy for potential mitigation of contractures, poor pliability, and textural irregularity. Patients also had chronic focal erosions or ulcerations despite professional wound care. All patients experienced incidental rapid healing of their chronic wounds within 2 weeks of their initial ablative fractional laser treatment. Healing was sustained throughout the treatment course and beyond and was associated with gradual enhancements in scar pliability, texture, durability, and range of motion. Conclusions: The unique pattern of injury associated with ablative fractional laser treatment may have various potential wound-healing advantages. These advantages include the novel concept of photomicrodebridement, including biofilm disruption and the stimulation of de novo growth factor secretion and collagen remodeling. If confirmed, ablative fractional resurfacing could be a potent new addition to traditional wound and scar treatment paradigms.

Original languageEnglish
Pages (from-to)1289-1293
Number of pages5
JournalArchives of Dermatology
Volume148
Issue number11
DOIs
StatePublished - Nov 1 2012

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Cicatrix
Wounds and Injuries
Contracture
Biofilms
Pliability
Lasers
Blast Injuries
Skin
Laser Therapy
Therapeutics
Articular Range of Motion
Wound Healing
Intercellular Signaling Peptides and Proteins
Collagen

ASJC Scopus subject areas

  • Dermatology

Cite this

Rapid healing of scar-associated chronic wounds after ablative fractional resurfacing. / Shumaker, Peter R.; Kwan, Julia M.; Badiavas, Evangelos V; Waibel, Jill; Davis, Stephen C; Uebelhoer, Nathan S.

In: Archives of Dermatology, Vol. 148, No. 11, 01.11.2012, p. 1289-1293.

Research output: Contribution to journalArticle

Shumaker, Peter R. ; Kwan, Julia M. ; Badiavas, Evangelos V ; Waibel, Jill ; Davis, Stephen C ; Uebelhoer, Nathan S. / Rapid healing of scar-associated chronic wounds after ablative fractional resurfacing. In: Archives of Dermatology. 2012 ; Vol. 148, No. 11. pp. 1289-1293.
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