Randomized controlled trial of a cognitive-behavioral intervention for HIV-positive persons: an investigation of treatment effects on psychosocial adjustment

Adam W. Carrico, Margaret A. Chesney, Mallory O. Johnson, Stephen F. Morin, Torsten B. Neilands, Robert H. Remien, Mary Jane Rotheram-Borus, F. Lennie Wong

Research output: Contribution to journalArticle

24 Scopus citations


Questions remain regarding the clinical utility of psychological interventions for HIV-positive persons because randomized controlled trials have utilized stringent inclusion criteria and focused extensively on gay men. The present randomized controlled trial examined the efficacy of a 15-session, individually delivered cognitive-behavioral intervention (n = 467) compared to a wait-list control (n = 469) in a diverse sample of HIV-positive persons who reported HIV transmission risk behavior. Five intervention sessions that dealt with executing effective coping responses were delivered between baseline and the 5 months post-randomization. Additional assessments were completed through 25 months post-randomization. Despite previously documented reductions in HIV transmission risk, no intervention-related changes in psychosocial adjustment were observed across the 25-month investigation period. In addition, there were no intervention effects on psychosocial adjustment among individuals who presented with mild to moderate depressive symptoms. More intensive mental health interventions may be necessary to improve psychosocial adjustment among HIV-positive individuals.

Original languageEnglish (US)
Pages (from-to)555-563
Number of pages9
JournalAIDS and Behavior
Issue number3
StatePublished - Jun 1 2009
Externally publishedYes



  • AIDS
  • Anxiety
  • Depression
  • HIV
  • Intervention
  • Positive affect

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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