Radionuclide cardiac stress testing

Purpose of Review: To briefly review the field of radionuclide stress imaging, including recent technologic advances and clinical applications. Recent Findings: ECG gating and attenuation correction help increase specificity and accuracy of myocardial single-photon emission computed tomography (SPECT) imaging. Furthermore, advances in camera hardware and software enable more rapid image acquisition and/or radiation dose reduction. Position emission tomography (PET) and hybrid imaging with computer tomography (CT) are emerging technologies which provide improved image resolution and complementary anatomical data. Nuclear cardiology also demonstrates a wide variety of prognostic applications for a diverse group of patient subgroups. More judicious use of SPECT technology using application of the recently updated appropriateness criteria is encouraged. Summary: Radionuclide stress imaging provides essential clinical information and has clear impact on patient assessment and management.