Radiographic progression of knee osteoarthritis in a Czech cohort

K. Pavelka, J. Gatterova, Roy D Altman

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective: To determine the 5-year radiographic progression of osteoarthritis (OA) of the knee in a Czech cohort. Methods: 139 patients with idiopathic OA were followed for 5 years, receiving only physical therapy and non-steroidal antiinflammatory drugs as needed. Weight-bearing radiographs of both knees were performed at the initial and final evaluation by a single technician using the same instrument and a standardized procedure. Radiographs were evaluated using the Kellgren-Lawrence scale (KL). Joint space width (JSW) was determined by 2 independent trained readers, and discrepancies re-reviewed. Results: JSW decreased 0.39 ± 0.95 mm in 5 years, or 0.078 ± 0.19 annually. The reduction of JSW was greatest in the KL grade III radiographs (0.099 ± 0,18 mm). The smallest reduction in JSW was seen in those with KL grade I (0.044 ± 0.14 mm). However, only 25% of those with KL stage II or stage III demonstrated any change in JSW over the 5-year period. The reduction in JSW was not constant, being most rapid in the first year and then much slower. The coefficient of variation (CV) of the method was good (intra- and inter-observer CV 3.6%). Conclusion: This 5-year follow up of Czech patients with OA of the knee demonstrated a low rate of radiographic progression of JSW. The most rapid progression appeared in KL stage III. The progression was most rapid in the first year. (C) Copyright Clinical and Experimental Rheumatology 2000.

Original languageEnglish (US)
Pages (from-to)473-477
Number of pages5
JournalClinical and Experimental Rheumatology
Volume18
Issue number4
StatePublished - 2000
Externally publishedYes

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Knee Osteoarthritis
Joints
Observer Variation
Weight-Bearing
Osteoarthritis
Knee
Anti-Inflammatory Agents
Pharmaceutical Preparations

Keywords

  • Knee osteoarthritis
  • Quantitative radiography
  • Radiographic progression

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Pavelka, K., Gatterova, J., & Altman, R. D. (2000). Radiographic progression of knee osteoarthritis in a Czech cohort. Clinical and Experimental Rheumatology, 18(4), 473-477.

Radiographic progression of knee osteoarthritis in a Czech cohort. / Pavelka, K.; Gatterova, J.; Altman, Roy D.

In: Clinical and Experimental Rheumatology, Vol. 18, No. 4, 2000, p. 473-477.

Research output: Contribution to journalArticle

Pavelka, K, Gatterova, J & Altman, RD 2000, 'Radiographic progression of knee osteoarthritis in a Czech cohort', Clinical and Experimental Rheumatology, vol. 18, no. 4, pp. 473-477.
Pavelka, K. ; Gatterova, J. ; Altman, Roy D. / Radiographic progression of knee osteoarthritis in a Czech cohort. In: Clinical and Experimental Rheumatology. 2000 ; Vol. 18, No. 4. pp. 473-477.
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