TY - JOUR
T1 - Radiofrequency ablation in primary non-small cell lung cancer
T2 - What a radiologist needs to know
AU - Bhatia, Shivank
AU - Pereira, Keith
AU - Mohan, Prasoon
AU - Narayanan, Govindarajan
AU - Wangpaichitr, Medhi
AU - Savaraj, Niramol
N1 - Publisher Copyright:
© 2016 Indian Journal of Radiology and Imaging.
PY - 2016/2
Y1 - 2016/2
N2 - Lung cancer continues to be one of the leading causes of death worldwide. In advanced cases of lung cancer, a multimodality approach is often applied, however with poor local control rates. In early non.small cell lung cancer (NSCLC), surgery is the standard of care. Only 15.30% of patients are eligible for surgical resection. Improvements in imaging and treatment delivery systems have provided new tools to better target these tumors. Stereotactic body radiation therapy (SBRT) has evolved as the next best option. The role of radiofrequency ablation (RFA) is also growing. Currently, it is a third.line option in stage 1 NSCLC, when SBRT cannot be performed. More recent studies have demonstrated usefulness in recurrent tumors and some authors have also suggested combination of RFA with other modalities in larger tumors. Following the National Lung Screening Trial (NLST), screening by low.dose computed tomography (CT) has demonstrated high rates of early.stage lung cancer detection in high.risk populations. Hence, even considering the current role of RFA as a third.line option, in view of increasing numbers of occurrences detected, the number of potential RFA candidates may see a steep uptrend. In view of all this, it is imperative that interventional radiologists be familiar with the techniques of lung ablation. The aim of this article is to discuss the procedural technique of RFA in the lung and review the current evidence regarding RFA for NSCLC.
AB - Lung cancer continues to be one of the leading causes of death worldwide. In advanced cases of lung cancer, a multimodality approach is often applied, however with poor local control rates. In early non.small cell lung cancer (NSCLC), surgery is the standard of care. Only 15.30% of patients are eligible for surgical resection. Improvements in imaging and treatment delivery systems have provided new tools to better target these tumors. Stereotactic body radiation therapy (SBRT) has evolved as the next best option. The role of radiofrequency ablation (RFA) is also growing. Currently, it is a third.line option in stage 1 NSCLC, when SBRT cannot be performed. More recent studies have demonstrated usefulness in recurrent tumors and some authors have also suggested combination of RFA with other modalities in larger tumors. Following the National Lung Screening Trial (NLST), screening by low.dose computed tomography (CT) has demonstrated high rates of early.stage lung cancer detection in high.risk populations. Hence, even considering the current role of RFA as a third.line option, in view of increasing numbers of occurrences detected, the number of potential RFA candidates may see a steep uptrend. In view of all this, it is imperative that interventional radiologists be familiar with the techniques of lung ablation. The aim of this article is to discuss the procedural technique of RFA in the lung and review the current evidence regarding RFA for NSCLC.
KW - Non-small cell lung cancer
KW - radiofrequency ablation
KW - stereotactic body radiation therapy
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U2 - 10.4103/0971-3026.178347
DO - 10.4103/0971-3026.178347
M3 - Review article
AN - SCOPUS:84961989718
VL - 26
SP - 81
EP - 91
JO - Indian Journal of Radiology and Imaging
JF - Indian Journal of Radiology and Imaging
SN - 0971-3026
IS - 1
ER -