Quantum dots as platforms for charge transfer-based biosensing: Challenges and opportunities

W. Russ Algar, Michael H. Stewart, Amy M Scott, Woohyun J. Moon, Igor L. Medintz

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Semiconductor quantum dots (QDs) have received significant attention as unique photoluminescent materials for biological imaging and sensing. Charge transfer (CT) modulation of QD emission has recently emerged as a promising detection modality in these applications; however, much still remains unknown about the mechanism through which an electron or hole transfers from a QD exciton to a redox active moiety in a bioconjugate construct. Here, we highlight the utility and challenges of CT for QD-based biosensing, particularly in comparison to Förster resonance energy transfer (FRET), and summarize the current understanding of this process, which is situated at the intersection between biological and photovoltaic research with QDs. This journal is

Original languageEnglish (US)
Pages (from-to)7816-7827
Number of pages12
JournalJournal of Materials Chemistry B
Volume2
Issue number45
DOIs
StatePublished - Dec 7 2014

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Quantum Dots
Semiconductor quantum dots
Charge transfer
Semiconductors
Energy Transfer
Excitons
Energy transfer
Oxidation-Reduction
Modulation
Electrons
Imaging techniques
Research

ASJC Scopus subject areas

  • Biomedical Engineering
  • Medicine(all)
  • Chemistry(all)
  • Materials Science(all)

Cite this

Quantum dots as platforms for charge transfer-based biosensing : Challenges and opportunities. / Algar, W. Russ; Stewart, Michael H.; Scott, Amy M; Moon, Woohyun J.; Medintz, Igor L.

In: Journal of Materials Chemistry B, Vol. 2, No. 45, 07.12.2014, p. 7816-7827.

Research output: Contribution to journalArticle

Algar, W. Russ ; Stewart, Michael H. ; Scott, Amy M ; Moon, Woohyun J. ; Medintz, Igor L. / Quantum dots as platforms for charge transfer-based biosensing : Challenges and opportunities. In: Journal of Materials Chemistry B. 2014 ; Vol. 2, No. 45. pp. 7816-7827.
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