Abstract
The objective of this study was to evaluate the application of acute phase protein assays for C-reactive protein, haptoglobin, and serum amyloid A, as well as protein electrophoresis, in ferrets. Samples from 41 clinically normal and 52 clinically abnormal pet ferrets were submitted from veterinary clinics within the United States. Reference intervals were calculated for all analytes from the clinically normal group using the robust method. The clinically abnormal group demonstrated significant elevations in the concentrations of the following analytes (. P < 0.05): total protein, alpha 2 globulins, beta globulins, gamma globulins, serum amyloid A, and haptoglobin. The preliminary results of this research investigation support a potential role for these acute phase protein assays to be used as adjunct tests for monitoring inflammation and disease in ferrets.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 201-208 |
| Number of pages | 8 |
| Journal | Journal of Exotic Pet Medicine |
| Volume | 24 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 1 2015 |
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Keywords
- Acute phase protein
- C-reactive protein
- Ferret
- Haptoglobin
- Protein electrophoresis
- Serum amyloid A
ASJC Scopus subject areas
- veterinary(all)
Cite this
Quantitation of Acute Phase Proteins and Protein Electrophoresis Fractions in Ferrets. / Ravich, Michelle; Johnson-Delaney, Cathy; Kelleher, Susan; Hess, Laurie; Arheart, Kristopher; Cray, Carolyn.
In: Journal of Exotic Pet Medicine, Vol. 24, No. 2, 01.04.2015, p. 201-208.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Quantitation of Acute Phase Proteins and Protein Electrophoresis Fractions in Ferrets
AU - Ravich, Michelle
AU - Johnson-Delaney, Cathy
AU - Kelleher, Susan
AU - Hess, Laurie
AU - Arheart, Kristopher
AU - Cray, Carolyn
PY - 2015/4/1
Y1 - 2015/4/1
N2 - The objective of this study was to evaluate the application of acute phase protein assays for C-reactive protein, haptoglobin, and serum amyloid A, as well as protein electrophoresis, in ferrets. Samples from 41 clinically normal and 52 clinically abnormal pet ferrets were submitted from veterinary clinics within the United States. Reference intervals were calculated for all analytes from the clinically normal group using the robust method. The clinically abnormal group demonstrated significant elevations in the concentrations of the following analytes (. P < 0.05): total protein, alpha 2 globulins, beta globulins, gamma globulins, serum amyloid A, and haptoglobin. The preliminary results of this research investigation support a potential role for these acute phase protein assays to be used as adjunct tests for monitoring inflammation and disease in ferrets.
AB - The objective of this study was to evaluate the application of acute phase protein assays for C-reactive protein, haptoglobin, and serum amyloid A, as well as protein electrophoresis, in ferrets. Samples from 41 clinically normal and 52 clinically abnormal pet ferrets were submitted from veterinary clinics within the United States. Reference intervals were calculated for all analytes from the clinically normal group using the robust method. The clinically abnormal group demonstrated significant elevations in the concentrations of the following analytes (. P < 0.05): total protein, alpha 2 globulins, beta globulins, gamma globulins, serum amyloid A, and haptoglobin. The preliminary results of this research investigation support a potential role for these acute phase protein assays to be used as adjunct tests for monitoring inflammation and disease in ferrets.
KW - Acute phase protein
KW - C-reactive protein
KW - Ferret
KW - Haptoglobin
KW - Protein electrophoresis
KW - Serum amyloid A
UR - http://www.scopus.com/inward/record.url?scp=84930764966&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84930764966&partnerID=8YFLogxK
U2 - 10.1053/j.jepm.2015.04.010
DO - 10.1053/j.jepm.2015.04.010
M3 - Article
AN - SCOPUS:84930764966
VL - 24
SP - 201
EP - 208
JO - Journal of Exotic Pet Medicine
JF - Journal of Exotic Pet Medicine
SN - 1557-5063
IS - 2
ER -