Quality of life in alopecia areata: A disease-specific questionnaire

G. Fabbrocini, L. Panariello, V. De Vita, C. Vincenzi, C. Lauro, D. Nappo, F. Ayala, Antonella Tosti

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Background Alopecia areata (AA) is an autoimmune disease affecting about 2% of the population, which has a considerable impact on quality of life (QoL). There are no disease-specific questionnaires to assess QoL in patients suffering from AA. Objective To validate a new disease-specific questionnaire for AA, named AA-QLI, and to compare the consequent Quality of Life Index (QLI) with the commonly known Dermatology Life Quality Index (DLQI) to verify if it can provide a more comprehensive tool for patients. Methods A total of 50 patients affected by AA were administered both the AA-QLI, created by us, and the well-known DLQI. With the aim to detect suitable QLI, we propose to use two multivariate analyses: a principal component analysis approach on the data collected with both questionnaires to compare their capability to measure the QoL; a structural equation modelling on our AA-QLI to identify which category of symptoms mostly affects the QoL. Results The scores of both the questionnaires are quite close, except for a few cases. Statistical analysis shows a higher specificity of the AA-QLI for evaluating QoL. Among the three areas in which AA-QLI is divided, 'Relationship' has a major impact on the QLI, followed by 'Subjective symptoms'; 'Objective signs' has a lower weight on the QLI. Conclusion AA-QLI is a good instrument to evaluate the real impact of AA on QoL. It can be helpful both for the physician and for the patient.

Original languageEnglish
JournalJournal of the European Academy of Dermatology and Venereology
Volume27
Issue number3
DOIs
StatePublished - Mar 1 2013
Externally publishedYes

Fingerprint

Alopecia Areata
Quality of Life
Surveys and Questionnaires
Dermatology

ASJC Scopus subject areas

  • Dermatology
  • Infectious Diseases

Cite this

Quality of life in alopecia areata : A disease-specific questionnaire. / Fabbrocini, G.; Panariello, L.; De Vita, V.; Vincenzi, C.; Lauro, C.; Nappo, D.; Ayala, F.; Tosti, Antonella.

In: Journal of the European Academy of Dermatology and Venereology, Vol. 27, No. 3, 01.03.2013.

Research output: Contribution to journalArticle

Fabbrocini, G. ; Panariello, L. ; De Vita, V. ; Vincenzi, C. ; Lauro, C. ; Nappo, D. ; Ayala, F. ; Tosti, Antonella. / Quality of life in alopecia areata : A disease-specific questionnaire. In: Journal of the European Academy of Dermatology and Venereology. 2013 ; Vol. 27, No. 3.
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